1.
Expanding therapeutic potential of Bdellovibrio bacteriovorus against multidrug-resistant pathogens.
Drug Discov Today
; 28(6): 103595, 2023 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37088356
RESUMO
Novel treatments toward Gram-negative bacteria are urgently needed to prevent even higher mortality levels associated with resistant bacterial infections. Predatory bacteria have been studied as a new type of treatment against pathogenic bacteria, including resistant species. However, because of limitations related to eradication efficacy, combination therapy using predatory bacteria with other agents has also been tested. Here, we discuss recent advances in the use of predatory bacteria to treat infections and propose novel combinatory strategies with antivirulence compounds.