RESUMO
The article considers the case of several years long increased level of activity of aspartate transaminase in blood plasma of clinically healthy persons from one family (belonging to Caucasioni type)--the father 35 years old and two biologic children, daughter 4 years old and son 3 years old. In all family members with hyper aspartate transaminasemia chronic diseases, alcohol and drugs consumption, regular use of certain medications and dietary supplements or impact of exogenous (ecologic) chemical factors producing persistent increase of activity of aspartate transaminase in blood plasma were totally excluded. On the basis of totality of anamnesis and results of clinical and laboratory examination the given condition was considered as "macro-AST" being a variant of biochemical phenomenon of "macro-enzymes".
Assuntos
Aspartato Aminotransferases/sangue , Família , Adulto , Pré-Escolar , Feminino , Humanos , Lactente , MasculinoRESUMO
Spectra of lectin-binding proteins of the human trophoblast were studied by the method affinity blotting using a set of loctins conjugated with peroxidase. The set included lectins Lens culinaris (LcL), Canavalia ensiformis (Con A), Ricinus communis (RCA 1), Arachis hypogaea (PNA), Triticum vulgaris (WGA), Laburnum anagyroides (LAL). Presence of N- and O-glycans in the composition of proteins of plasmatic membranes of a trophoblast was shown, partial characteristics of their oligosugar chains being presented. Sialic acids were established to be absent in the composition of alkaline phosphatase of mature placenta.