RESUMO
Ameloblastoma is a benign locally aggressive type of odontogenic tumor derived exclusively from the epithelium. Histologically, ameloblastoma is classified into many variants, of which granular cell ameloblastoma (GCA) is a rare type, characterized by nest of large eosinophilic granular cells. This article describes a case of GCA in a 50-year-old female patient with clinical, radiological, and histological features along with a systematic review of the literature.
Assuntos
Ameloblastoma/patologia , Tumor de Células Granulares/patologia , Neoplasias Maxilomandibulares/patologia , Ameloblastoma/diagnóstico , Ameloblastoma/cirurgia , Ameloblastoma/ultraestrutura , Diagnóstico Diferencial , Feminino , Tumor de Células Granulares/diagnóstico , Tumor de Células Granulares/cirurgia , Tumor de Células Granulares/ultraestrutura , Humanos , Neoplasias Maxilomandibulares/diagnóstico , Neoplasias Maxilomandibulares/cirurgia , Neoplasias Maxilomandibulares/ultraestrutura , Osteotomia Mandibular , Pessoa de Meia-Idade , Fotomicrografia , Procedimentos de Cirurgia Plástica , Resultado do TratamentoRESUMO
Myoepithelial cells (MECs) are considered to be a key participant in most salivary gland diseases, particularly tumors. MECs structurally resemble both epithelial cells and smooth muscles. Diagnostic dilemmas caused are due to inadequacy of characterizing the wide spectrum of morphologic and immunologic features which are different for both normal and neoplastic MECs. This article discusses the development, functions and structure of both normal and neoplastic MECs, their staining properties and differences in the morphologic and immunophenotypic properties of the MEC in detail. It also describes the role of MEC in pathogenesis and morphogenesis of various nonneoplastic and neoplastic salivary gland lesions and thereby are responsible for the myriad histopathology of salivary gland tumors.
