Blueprint for the development of a community-based hospital biorepository.

In recent years, the focus of research on human disease has shifted to the molecular level to determine genetic and proteome expression variations among humans as well as during disease development and progression. This trend, along with the many technological advances in the biomedical field, requires the availability of high-quality human specimen and accompanying clinical data. Therefore, a well-planned, quality-controlled biorepository is a critical resource in furthering the advances of biomedical discoveries. This article describes the considerations and decisions needed to obtain and store high-quality specimen and accompanying clinical data in a biorepository.