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1.
Arch Environ Contam Toxicol ; 75(4): 503-511, 2018 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-30056617

RESUMO

Lead exposure is an unresolved pediatric health risk and disproportionately affects children in lower-income neighborhoods. Residences with children younger than age 5 years are the focus of mitigation policies; however, studies have shown that older children between the ages of 5 and 12 years also are at risk of central nervous system effects. Whether historically contaminated neighborhoods present ongoing risk to older children also is of concern. This study compared the blood lead levels (BLLs) of older children from an historically contaminated urban neighborhood to those of demographically matched children from a nearby rural locale and predicted significantly higher BLLs in the urban children. The study included 222 children aged 5-12 years, 111 from the urban neighborhood and 111 from local rural townships, matched for age, sex, race/ethnicity, and family income. Blood lead, cadmium, and mercury were measured using inductively coupled plasma mass spectrometry. General linear models tested whether geographic location (urban vs. rural) predicted child heavy metal levels, controlling for sex and age. Only location predicted only child BLL (R2= 0.36); children living in the urban setting had significantly higher BLLs as compared with matched rural township children (F = 125, df220,2, p <0.001). Neighborhoods with a history of lead contamination can present current risk of lead exposure for older children between the ages of 5 and 12 years, as well as for infants and toddlers. More studies are needed to better characterize the risk of lead exposure to older children, particularly in lower-income neighborhoods with a history of lead contamination.


Assuntos
Exposição Ambiental/análise , Chumbo/sangue , Cádmio/sangue , Criança , Pré-Escolar , Feminino , Habitação , Humanos , Lactente , Intoxicação por Chumbo/sangue , Modelos Lineares , Masculino , Mercúrio/sangue , População Rural , Texas , População Urbana
2.
BMC Public Health ; 17(1): 850, 2017 10 27.
Artigo em Inglês | MEDLINE | ID: mdl-29078766

RESUMO

BACKGROUND: In a previously conducted Health Impact Assessment of a well-water dependent southwest community, arsenic (As) levels greater than the EPA Maximum Contaminant Level (10 µg/L) were identified in home water samples. The goals of this study were to test whether children from the previously studied well-water dependent community (Community 1) had higher blood As levels than children from a demographically similar and geographically nearby community dependent on a municipal water supply (Community 2); to test whether home water As levels predicted child As blood levels; and to examine how child As blood levels changed over time. METHODS: This was an observational study of 252 children aged 4 to 12 years from two communities. Children were recruited through elementary schools and tested during the school day; 204 children participated in follow-up testing. Home water samples were collected according to U.S. Environmental Protection agency recommended procedures. Child heavy metal blood levels and home water sample heavy metal levels were analyzed using inductively coupled plasma mass spectrometry. General linear regression analysis was used to test the influence of community on child As levels, and to examine the contribution of home water As levels to child blood As levels. RESULTS: Arsenic was detectable in all children tested. Blood levels ranged from 0.09-2.61 µg/dL; approximately 31% of children tested at Time I (79/252) had blood As values above the current acceptable limit (1.2 µg/dL). Approximately 8% of household water samples (6/76) had As levels higher than 10 µg/L. Community did not predict child blood As levels; seasonal effects differed by Community. At Time II, child blood As levels were higher in Community 2 than in Community 1. CONCLUSION: A large proportion of children in the communities tested had As exposure. Home water As levels did not predict child blood As levels. Fluctuating child blood As levels by season and over time suggested the contribution of multiple factors and the need for further studies.


Assuntos
Arsênio/análise , Exposição Ambiental/análise , População Rural , Poluentes Químicos da Água/análise , Abastecimento de Água/estatística & dados numéricos , Arsênio/sangue , Criança , Pré-Escolar , Feminino , Humanos , Masculino , População Rural/estatística & dados numéricos , Texas , Poços de Água
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