Phenotypic description of cardiac findings in a population of Dogue de Bordeaux with an emphasis on atrial fibrillation.

The aim of this study was to describe the clinical phenotype of Dogue de Bordeaux (DdB) referred for cardiac investigation, with particular reference to the prevalence of atrial fibrillation and associated features. Review of canine medical records of two United Kingdom veterinary referral hospitals identified 64 DdB with available echocardiographic and electrocardiographic (ECG)/Holter data. Atrial fibrillation was documented in 25 (39%) dogs and supraventricular tachycardia was recorded in five (7.8%) dogs. In a subset of 34 dogs, excluding congenital heart disease (n=17), presence of a cardiac mass (n=7) and non-cardiac neoplasia (n=6), 19 (56%) dogs had atrial fibrillation, with a median heart rate of 200 beats per min (bpm) on presentation. Atrial fibrillation was inconsistently associated with cardiac chamber remodelling, but was frequently associated with systolic dysfunction (13/19, 68.4%) and right sided atrial or ventricular dilatation (14/19, 73.7%) in dogs with atrial fibrillation in this subset. No dogs in this subset had right sided atrial or ventricular dilatation in the absence of supraventricular arrhythmia or systolic dysfunction. The absence of structural heart disease in some dogs with supraventricular arrhythmias suggests that an underlying primary arrhythmic process might be responsible for initiating remodelling, although a primary cardiomyopathy cannot be ruled out.

An online health survey of Dogue de Bordeaux owners and breeders with special emphasis on cardiac disease.

A questionnaire-based study was undertaken to assess health problems affecting the Dogue de Bordeaux breed of dog and, in particular, the potential impact of cardiac disease. An online survey tool was used to design a questionnaire for Dogue de Bordeaux owners and breeders. After 1year of response time, information was collected on 278 dogs owned by 215 individuals, mostly based in the United Kingdom. Of the 278 dogs, veterinary attention had been sought for chronic skin disease in 63 (22.7%), lameness in 43 (15.5%), gastrointestinal signs in 37 (13.3%) and neoplasia in 28 (10.1%). Cardiac disease was reported in 13/278 dogs (4.7%). At the time of completion of the survey, 55 (19.8%) dogs were dead, 17 (31%) of which were reported to have died suddenly and unexpectedly. Respondents expressed interest in a formal cardiac health screening scheme in the Dogue de Bordeaux breed, but would be reluctant to volunteer for such a scheme if information on disease detected during screening was open access. The incidence of sudden unexpected death was high; although there was no corroboration that the sudden deaths were related to cardiac disease, a possible connection should be explored further.