Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 13 de 13
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
1.
Children (Basel) ; 10(2)2023 Feb 09.
Artigo em Inglês | MEDLINE | ID: mdl-36832458

RESUMO

Objective. To determine the acceptability of using extended reality (XR) relaxation training as a preventive treatment for pediatric migraine. Methods. Youths aged 10-17 years old with migraine were recruited from a specialty headache clinic and completed baseline measures evaluating their vestibular symptoms and attitudes about technology. The patients were then instructed in three XR-based relaxation training conditions (fully immersive virtual reality with and without neurofeedback, and augmented reality with neurofeedback), in counterbalanced order, and completed acceptability and side effect questionnaires after each. The patients also took XR equipment home for one week to use for relaxation practice and again completed the measures about their experience. The acceptability and side effect data were compared against predetermined acceptable thresholds and were evaluated for their association with the participant characteristics. Results. The aggregate acceptability questionnaire scores exceeded our minimum threshold of 3.5/5, with the two fully immersive virtual reality conditions preferred over augmented reality for relaxation training (z = -3.02, p = 0.003, and z = -2.31, p = 0.02). The endorsed side effects were rated by all but one participant as mild, with vertigo being the most common. The acceptability ratings were not reliably associated with age, sex, typical hours per day of technology use, or technology attitudes, but were inversely related to the side effect scores. Conclusions. The preliminary data on acceptability and tolerability of immersive XR technology for relaxation training among youths with migraine supports further intervention development work.

2.
Pain Med ; 20(8): 1600-1610, 2019 08 01.
Artigo em Inglês | MEDLINE | ID: mdl-30690591

RESUMO

OBJECTIVE: To assess conditioned pain modulation efficiency in persons with and without migraine headaches. DESIGN: Cross-sectional assessment of experimental pain. SETTING: University campus and surrounding community in a large Midwestern US city. SUBJECTS: Twenty-three adults with and 32 without a history of migraine headaches participated in the study. Participants were mostly female (N = 40) with an average age of 23 years. METHODS: Four electrocutaneous stimulations of the supraorbital branch of the left trigeminal nerve were delivered at 150% of an individually determined pain threshold. Conditioned pain modulation was assessed by applying a noxious counterstimulus (forearm ischemia) and delivering four more electrocutaneous stimulations. After each stimulation, pain and the nociceptive blink reflex were assessed. Depression and pain catastrophizing were assessed to control for the potential influence of these variables on pain modulation. RESULTS: Participants with and without migraine headaches had similar baseline pain responsivity, without significant differences in pain report or nociceptive blink reflexes. Pain report was inhibited by conditioned pain modulation in both the migraine and control groups. However, unlike nonmigraine controls, participants with migraines did not exhibit an inhibition of nociceptive blink reflexes during the ischemia task. This pattern persisted after controlling for level of pain catastrophizing and depression. CONCLUSIONS: Migraine sufferers exhibited impaired conditioned pain modulation of the nociceptive blink reflex, suggesting a deficiency in inhibition of trigeminal nociception, which may contribute to the development of migraine headaches.


Assuntos
Piscadela/fisiologia , Condicionamento Psicológico/fisiologia , Transtornos de Enxaqueca/fisiopatologia , Nociceptividade/fisiologia , Limiar da Dor/fisiologia , Dor/fisiopatologia , Nervo Trigêmeo/fisiopatologia , Adolescente , Adulto , Estudos de Casos e Controles , Catastrofização , Depressão , Feminino , Antebraço/irrigação sanguínea , Humanos , Isquemia/fisiopatologia , Masculino , Medição da Dor , Adulto Jovem
3.
Nurs Res ; 61(6): 441-5, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-22960585

RESUMO

BACKGROUND: Rates of postpartum depression have been found to be significantly higher in mothers of infants in the neonatal intensive care unit (NICU) than the general population estimate of 10%-15%, making routine screening for these mothers essential. OBJECTIVES: The aim of this study was to examine the reliability (internal consistency) and construct validity of the Postpartum Depression Screening Scale with a sample of mothers of infants in the NICU. METHODS: A total of 111 (40% of eligible) mothers participated in the study. Mothers completed a brief demographic questionnaire and the screening scale at 14 or greater days postpartum. Estimates of internal consistency were evaluated using Cronbach's coefficient alpha. RESULTS: On the basis of the scale total score, 52% of mothers had a positive screen and an additional 30% received a score indicating that they were at-risk. Reliability estimates were consistent with previous research and indicate excellent internal consistency for the total score and adequate to good internal reliability for subscales scores. The coefficient alpha for total score equaled .95, and alpha for subscale scores ranged from .72 (Anxiety/Insecurity) to .89 (Suicidal Thoughts). Interscale correlations were consistently lower than subscale reliability estimates (coefficient alpha) and were lower than subscale-to-total score correlations, suggesting initial support for the proposed structure of the scale for mothers in the NICU. DISCUSSION: Most of this sample of mothers experienced significant symptoms of postpartum depression. The Postpartum Depression Screening Scale is a promising tool for screening mothers with infants in the NICU. Additional research is necessary to better understand the construct and predictive validity of scores among these mothers. Current and future research will contribute to the routine use of scale as a screening tool in this environment.


Assuntos
Depressão Pós-Parto/diagnóstico , Unidades de Terapia Intensiva Neonatal , Programas de Rastreamento/métodos , Escalas de Graduação Psiquiátrica , Adolescente , Adulto , Pesquisa em Enfermagem Clínica , Feminino , Humanos , Recém-Nascido , Reprodutibilidade dos Testes , Adulto Jovem
4.
J Clin Sleep Med ; 7(6): 622-31, 2011 Dec 15.
Artigo em Inglês | MEDLINE | ID: mdl-22171201

RESUMO

STUDY OBJECTIVES: Evidence supports the use of cognitive behavioral therapies for nightmares in trauma-exposed individuals. This randomized clinical trial replicated a study of exposure, relaxation, and rescripting therapy(ERRT) and extended prior research by including broad measures of mental health difficulties, self-reported physical health problems, and quality of life. Additionally, physiological correlates of treatment-related change assessed from a script-driven imagery paradigm were examined. METHODS: Forty-seven individuals were randomized to treatment or waitlist control. RESULTS: The treatment group demonstrated improvements relative to the control group at the one-week post-treatment assessment. At the 6-month follow-up assessment, significant improvements were found for frequency and severity of nightmares, posttraumatic stress disorder symptoms, depression, sleep quality and quantity, physical health symptoms, anger, dissociation, and tension reduction behaviors. Participants also reported improved quality of life. Treatment-related decreases in heart rate to nightmare imagery were correlated with improvements in sleep quality and quantity; treatment-related decreases in skin conductance to nightmare imagery were correlated with improvements in nightmare severity, posttraumatic stress disorder symptom severity, sleep quality, and fear of sleep; and treatment-related decreases in corrugator activity to nightmare imagery were correlated with improved physical health. CONCLUSIONS: Findings provide additional support for the use of ERRT in treating nightmares and related difficulties and improving sleep.


Assuntos
Terapia Cognitivo-Comportamental/métodos , Sonhos/psicologia , Imagens, Psicoterapia , Relaxamento/psicologia , Transtornos do Sono-Vigília/terapia , Transtornos de Estresse Pós-Traumáticos/complicações , Adulto , Doença Crônica , Eletroencefalografia , Feminino , Seguimentos , Humanos , Pessoa de Meia-Idade , Testes Neuropsicológicos , Valor Preditivo dos Testes , Valores de Referência , Medição de Risco , Índice de Gravidade de Doença , Transtornos do Sono-Vigília/etiologia , Transtornos de Estresse Pós-Traumáticos/diagnóstico , Transtornos de Estresse Pós-Traumáticos/terapia , Resultado do Tratamento , Adulto Jovem
5.
J Pain ; 11(12): 1429-41, 2010 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-20554479

RESUMO

UNLABELLED: Sex differences in the processing and experience of emotion exist. The present study examined whether sex differences in emotion lead to sex differences in affective modulation of pain and spinal nociception (assessed by nociceptive flexion reflex, NFR). Participants were healthy men (n = 47) and women (n = 73). Prior to affective modulation testing, electrocutaneous pain sensitivity was assessed (NFR threshold, pain threshold, pain tolerance). Affective modulation of pain and NFR was then assessed by presenting pictures that vary in emotional valence and arousal (mutilation, attack, death, neutral, families, adventure, erotica) during which suprathreshold electrocutaneous stimulations were delivered. Subjective emotional reactions were assessed after every picture, and nociceptive reactions were assessed after every suprathreshold stimulus. Results indicated women had greater pain sensitivity and also responded more negatively to attack pictures and less positively to erotic pictures. But despite these differences, affective modulation of pain/NFR was not moderated by sex: erotic pictures inhibited pain/NFR and mutilation pictures enhanced pain/NFR. Together, this implies subjective emotional experience does not completely mediate picture-evoked modulation of pain/NFR, a supposition that was further supported by exploratory analyses that demonstrated picture-evoked modulation of pain/NFR was present even after controlling for intra- and inter-individual differences in emotional reactions to pictures. Implications and limitations of these findings are discussed. PERSPECTIVE: Evidence suggests that women are more sensitive to experimental and clinical pain, but the mechanisms contributing to these sex differences are poorly understood. Affective processes are known to play a role in regulating pain signaling and pain experience; therefore, the present study examined whether sex differences in affective experience contribute to sex differences in pain. Results indicate that in healthy individuals affective processes may not contribute to sex differences in pain.


Assuntos
Emoções/fisiologia , Limiar da Dor/psicologia , Dor/psicologia , Caracteres Sexuais , Adulto , Estimulação Elétrica , Feminino , Humanos , Masculino , Nociceptores/fisiologia , Dor/fisiopatologia , Limiar da Dor/fisiologia , Reflexo/fisiologia
6.
J Clin Psychol ; 66(4): 365-82, 2010 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-20127794

RESUMO

Cognitive-behavioral treatments (CBTs) that target nightmares are efficacious for ameliorating self-reported sleep problems and psychological distress. However, it is important to determine whether these treatments influence objective markers of nightmare-related fear, because fear and concomitant physiological responses could promote nightmare chronicity and sleep disturbance. This randomized, controlled study (N=40) assessed physiological (skin conductance, heart rate, facial electromyogram) and subjective (displeasure, fear, anger, sadness, arousal) reactions to personally relevant nightmare imagery intended to evoke nightmare-related fear. Physiological assessments were conducted at pretreatment as well as 1-week, 3-months, and 6-months posttreatment. Results of mixed effects analysis of variance models suggested treatment reduced physiological and subjective reactions to nightmare imagery, gains that were generally maintained at the 6-month follow-up. Potential implications are discussed.


Assuntos
Terapia Cognitivo-Comportamental/métodos , Sonhos/fisiologia , Transtornos de Estresse Pós-Traumáticos/fisiopatologia , Transtornos de Estresse Pós-Traumáticos/terapia , Estresse Psicológico/fisiopatologia , Estresse Psicológico/terapia , Adulto , Análise de Variância , Doença Crônica , Depressão/fisiopatologia , Depressão/psicologia , Sonhos/psicologia , Medo/fisiologia , Medo/psicologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Monitorização Fisiológica , Transtornos de Estresse Pós-Traumáticos/complicações , Transtornos de Estresse Pós-Traumáticos/psicologia , Estresse Psicológico/psicologia , Inquéritos e Questionários , Resultado do Tratamento
7.
J Pain ; 10(8): 860-9, 2009 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-19638330

RESUMO

UNLABELLED: Existing evidence indicates that pain catastrophizing is associated with enhanced pain reports and lower pain threshold/tolerance levels, but is not significantly related to nociceptive flexion reflex (NFR) threshold in healthy and clinical pain samples. This suggests pain catastrophizing may modulate pain threshold at a supraspinal level without influencing descending modulation of spinal nociceptive inputs. To examine this issue further, the present study assessed NFR threshold, electrocutaneous pain threshold, and electrocutaneous pain tolerance, as well as subjective ratings of noxious stimuli in a sample of 105 healthy adults. Pain catastrophizing was assessed prior to testing using traditional instructions and after pain testing with instructions to report on cognitions during testing (situation-specific catastrophizing). As expected, NFR threshold was correlated with pain sensitivity measures, but uncorrelated with both measures of catastrophizing. Although situation-specific catastrophizing was correlated with some pain outcomes, neither catastrophizing measure (traditional or situation specific) moderated the relationship between NFR and pain sensitivity. These findings confirm and extend existing evidence that catastrophizing influences pain reports through supraspinal mechanisms (eg, memory, report bias, attention) without altering transmission of spinal nociceptive signals. PERSPECTIVE: Assessing catastrophic thoughts related to a specific painful event (situation-specific catastrophizing) provides important additional information regarding the negative cognitions that influence pain-related processes. However, neither situation-specific nor traditionally measured pain catastrophizing appear to enhance pain by engaging descending controls to influence spinal nociceptive processes.


Assuntos
Limiar da Dor , Dor/psicologia , Reflexo , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Estimulação Elétrica , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Modelos Psicológicos , Medição da Dor , Testes Psicológicos , Caracteres Sexuais , Adulto Jovem
8.
Psychophysiology ; 46(5): 939-48, 2009 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-19497013

RESUMO

Physiological reactions to noxious stimuli are often used to make inferences about pain, but few studies have thoroughly examined the intra- and interindividual relationships between them. In the present study (N=104), multilevel analyses was used to assess relations between physiological (nociceptive flexion reflex magnitude [NFR], blink reflex magnitude, skin conductance response [SCR], heart rate [HR]) and subjective reactions to electrocutaneous stimuli. All physiological reactions were significant predictors of ratings when entered alone, explaining 1% (SCR) to 29% (NFR) of the variance; but only NFR, blink, and HR were significant in a multivariate predictor model. Significant interindividual variability in slopes was found for blink and HR, but not NFR. A final trimmed model that included NFR, blink, and the blink random slope explained 35% of the variance in ratings.


Assuntos
Nociceptores/fisiologia , Medição da Dor , Dor/fisiopatologia , Adulto , Algoritmos , Interpretação Estatística de Dados , Estimulação Elétrica , Feminino , Hemodinâmica/fisiologia , Humanos , Individualidade , Masculino , Modelos Psicológicos , Modelos Estatísticos , Valor Preditivo dos Testes , Reflexo de Sobressalto/fisiologia , Reprodutibilidade dos Testes
9.
Behav Sleep Med ; 6(3): 158-77, 2008.
Artigo em Inglês | MEDLINE | ID: mdl-18629687

RESUMO

Script-driven imagery was used to assess nightmare imagery-evoked physiological-emotional reactivity (heart rate, skin conductance, facial electromyogram, subjective ratings) in trauma-exposed persons suffering from chronic nightmares. Goals were to determine the efficacy of nightmare imagery to evoke physiological-emotional reactivity, correlates (mental health, nightmare characteristics) of reactivity, and consequences (sleep and health problems) of reactivity. Nightmare imagery resulted in significant reactivity relative to control imagery. No mental health variable (posttraumatic stress disorder status, depressive symptoms, dissociation) or nightmare characteristic (months experienced, frequency, similarity to trauma) was associated with reactivity level. However, nightmare imagery-evoked autonomic responses were associated with greater sleep disturbance and reported health symptoms, even when nightmare frequency was controlled. These results suggest nightmare-related autonomic reactions may contribute to sleep and health disturbance.


Assuntos
Sonhos , Imaginação , Transtornos de Estresse Pós-Traumáticos/epidemiologia , Transtornos de Estresse Pós-Traumáticos/psicologia , Adulto , Terapia Cognitivo-Comportamental , Eletromiografia , Músculos Faciais , Feminino , Resposta Galvânica da Pele , Frequência Cardíaca/fisiologia , Humanos , Masculino , Pessoa de Meia-Idade , Recidiva , Transtornos de Estresse Pós-Traumáticos/diagnóstico , Inquéritos e Questionários
10.
Pain ; 136(3): 250-261, 2008 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-17703886

RESUMO

Prior research suggests emotional picture-viewing modulates motoric (nociceptive flexion reflex), autonomic (skin conductance response, heart rate acceleration), and subjective (pain rating) reactions to noxious electrodermal stimulation. The present study sought to determine whether emotional valence and arousal contribute to nociception modulation. To do so, pictures varying in emotional content (erotica, food, neutral, loss, attack) were chosen to manipulate emotional valence (pleasant=erotic and food; unpleasant=loss and attack) and arousal (low=food and loss; moderate=erotica and attack). Pictures were presented in pseudorandom order to elicit emotional processing while noxious electric stimulations were delivered to the sural nerve. Nociceptive flexion reflex (NFR) magnitude, skin conductance response (SCR), heart rate (HR) acceleration, and subjective pain ratings to each stimulation were measured, standardized, averaged by picture content, and analyzed. Results suggested that picture-viewing explained 52% of the variance in the multivariate combination of the nociceptive reactions and modulated them in parallel. Pleasant pictures inhibited reactions, whereas unpleasant pictures enhanced them. However, only erotica and attack pictures elicited significant modulation relative to neutral pictures, suggesting arousal also contributed. An exploratory multilevel analysis also supported this conclusion. Together, these data suggest emotional control of nociceptive reactions (ECON) is associated with a valence-by-arousal interaction. Implications of these findings for how emotional picture-viewing can be used to study supraspinal modulation are discussed.


Assuntos
Afeto/fisiologia , Nível de Alerta/fisiologia , Biorretroalimentação Psicológica/fisiologia , Emoções/fisiologia , Limiar da Dor/fisiologia , Limiar da Dor/psicologia , Adulto , Feminino , Humanos , Masculino , Nociceptores/fisiologia
11.
Int J Psychophysiol ; 63(1): 105-9, 2007 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-17049399

RESUMO

Research suggests that emotion modulates spinal nociception and pain; however, there is limited evidence that other objective, nociceptive reactions are modulated. This study examined the impact of affective picture-viewing on autonomic reactions (skin conductance response, heart rate acceleration) resulting from noxious electric stimulations to the sural nerve. Pictures varying in affective valence (unpleasant, neutral, pleasant) were presented during which noxious stimulations were delivered. Skin conductance response and short-latency heart rate acceleration following each stimulation was calculated and averaged by picture valence. Results suggested that autonomic reactions were modulated in parallel. Specifically, reactions were smaller during pleasant pictures than unpleasant pictures, although unpleasant pictures did not result in significant facilitation relative to neutral pictures. The valence linear trend explained 26% of the variance in the multivariate combination of the reactions, suggesting emotion does modulate autonomic reactions to nociception. These results suggest that SCR and HR acceleration are outcomes that can be assessed together with NFR and pain report during picture-viewing to study affective modulation of spinal (NFR), supraspinal (SCR, HR acceleration), and subjective (pain report) nociceptive reactions.


Assuntos
Afeto/fisiologia , Sistema Nervoso Autônomo/fisiologia , Nociceptores/fisiopatologia , Limiar da Dor/fisiologia , Adolescente , Adulto , Estimulação Elétrica/efeitos adversos , Feminino , Resposta Galvânica da Pele/fisiologia , Frequência Cardíaca/fisiologia , Humanos , Masculino , Análise Multivariada , Estimulação Luminosa , Tempo de Reação
12.
Pain ; 126(1-3): 221-33, 2006 Dec 15.
Artigo em Inglês | MEDLINE | ID: mdl-16890356

RESUMO

Recent evidence suggests that emotional picture-viewing is a reliable method of engaging descending modulation of spinal nociception. The present study attempted to replicate these findings and determine the effect of noxious stimulus predictability. Participants viewed pictures from the International Affective Picture System (IAPS), during which pain and nociceptive flexion reflexes (NFR) were elicited by electric shocks delivered to the sural nerve. For half of the participants (n=25) shocks were preceded by a cue (predictable), whereas the other half received no cue (unpredictable). Results suggested emotion was successfully induced by pictures, but the effect of picture-viewing on the NFR was moderated by the predictability of the shocks. When shock was unpredictable, spinal nociception (NFR) and pain ratings were modulated in parallel. Specifically, pain and NFR magnitudes were lower during pleasant emotions and higher during unpleasant emotions. However, when shocks were predictable, only pain was modulated in this way. NFRs from predictable shocks were not altered by pictures. Further, exploratory analyses found that pain ratings, but not NFRs, were lower during predictable shocks. These data suggest emotional picture-viewing is a reliable method of engaging descending modulation of spinal nociception. However, descending modulation could not be detected in NFRs resulting from predictable noxious stimuli. Although preliminary, this study implies that separate mechanisms are responsible for emotional modulation of nociception at spinal vs. supraspinal levels, and that predictable noxious events may disengage modulation at the spinal level. The current paradigm could serve as a useful tool for studying descending modulation.


Assuntos
Sinais (Psicologia) , Eletrochoque , Emoções , Nociceptores/fisiopatologia , Dor/fisiopatologia , Dor/psicologia , Medula Espinal/fisiopatologia , Adulto , Feminino , Humanos , Masculino , Dor/etiologia , Medição da Dor , Estimulação Luminosa , Reflexo , Nervo Sural
13.
Psychophysiology ; 42(5): 579-87, 2005 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-16176380

RESUMO

This study was designed to examine the effect of emotion on the nociceptive flexion reflex and pain ratings. To do so, 28 participants viewed pictures varying in emotional valence (unpleasant, neutral, pleasant) and electric stimulations were delivered during and in between pictures. Biceps femoris EMG resulting from the stimulations was used to quantify the nociceptive flexion reflex (spinal nociception), and pain ratings to the stimulations were used as an evaluative measure of supraspinal nociception. Manipulation checks suggested that pictures effectively manipulated emotion. Moreover, nociceptive flexion reflex magnitudes and pain ratings were modulated in a parallel manner. Specifically, viewing unpleasant pictures enhanced the nociceptive flexion reflex and pain, whereas viewing pleasant pictures inhibited the reflex and pain. Analyses suggested that emotional valence, but not arousal, mediated the effects of pictures.


Assuntos
Afeto/fisiologia , Encéfalo/fisiologia , Eletromiografia , Limiar da Dor/fisiologia , Reflexo/fisiologia , Medula Espinal/fisiologia , Adolescente , Adulto , Nível de Alerta/fisiologia , Estimulação Elétrica , Reação de Fuga/fisiologia , Feminino , Resposta Galvânica da Pele/fisiologia , Humanos , Masculino , Motivação , Inibição Neural/fisiologia , Estatística como Assunto
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...