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1.
Am J Ophthalmol Case Rep ; 28: 101744, 2022 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-36393908

RESUMO

Purpose: To report a case of an exogenous endophthalmitis caused by the fungal species Glomerella cingulata. Observations: A 71-year-old male presented with an infectious keratitis that evolved into endophthalmitis. Combined cataract extraction and pars plana vitrectomy was performed and the vitreous specimen cultured Glomerella cingulata, a variant of the Colletotrichum gloeosporioides fungal species. Despite early treatment with topical, systemic and intravitreal doses of both voriconazole and amphotericin B, the patient had a poor visual and anatomical outcome. Conclusions and Importance: Glomerella cingulata may rarely cause endophthalmitis with devastating visual outcomes.

2.
Int Med Case Rep J ; 13: 569-572, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33173353

RESUMO

BACKGROUND: Panophthalmitis is a severe inflammation of the globe that can result as a rare complication of ophthalmic surgery. In severe cases, it may also be associated with orbital inflammation and cavernous sinus thrombosis. PURPOSE: This case demonstrates a rare and life-threatening post-operative complication of cataract surgery. We also hope to highlight the importance of considering the relevant risk factors associated with developing potential infections after cataract surgery, including the use of corneal sutures, high-risk behaviours such as excessive eye-rubbing, and non-compliance with appointments and post-operative medications. CASE REPORT: We report the case of a 35-year-old female with severe autism and developmental delay who developed panophthalmitis, orbital inflammation and cavernous sinus thrombosis 6 weeks post cataract surgery. The likely cause was corneal suture-related microbial keratitis, and the patient required enucleation due to sepsis. CONCLUSION: Post-surgical panophalmitis is a rapidly progressive disease that is not only sight- but life-threatening and demands urgent and intensive treatment. Consideration of early enucleation may be required to prevent deterioration in such patients.

3.
Mycoses ; 63(1): 43-51, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31556179

RESUMO

To describe the clinical features, management and outcomes in patients with fungal keratitis at the Sydney Eye Hospital, Australia, over a 9-year period to guide appropriate initial therapy. A retrospective case review was conducted. Patients diagnosed with fungal keratitis from 1 January 2009 to 31 December 2017 were identified from hospital coding and pathology databases. Data were extracted from the medical records. A total of 55 episodes from 51 patients were included. Mean age was 60 ± 20 years (range: 19-91 years), and 33 were male. The fungal species was not identified in two patients. Predisposing factors included ocular surface disease in 17 eyes (32%); corneal disease, 15 (28%); corneal trauma, 12 (23%); and contact lens wear, 13 (24.5%). Fusarium spp. (15, 27%) and Candida parapsilosis (10, 18%) were the most common isolates. The median visual acuity at presentation was 1.3 logMAR (range: 0 to 3) and after treatment 0.7 logMAR (range: -0.02 to 3) (P = .008). Despite medical therapy, most commonly with natamycin and topical and oral voriconazole, surgical intervention was required in 21 eyes (40%); including antifungal injections in 9 (16%); corneal transplantation, 16 (30%); evisceration, 2 (4%); and enucleation, 1 (2%). A poor visual outcome was recorded in 27 of 43 (63%) patients. Fungal keratitis remains a cause of significant ocular morbidity; the majority of patients face a poor outcome despite intense medical and at times surgical treatment. In our setting, fungal keratitis was more commonly associated with corneal or ocular surface disease.


Assuntos
Doenças da Córnea/complicações , Infecções Oculares Fúngicas , Ceratite/microbiologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Antifúngicos/uso terapêutico , Austrália , Candida parapsilosis/isolamento & purificação , Lentes de Contato/microbiologia , Córnea/microbiologia , Córnea/patologia , Doenças da Córnea/microbiologia , Infecções Oculares Fúngicas/tratamento farmacológico , Infecções Oculares Fúngicas/microbiologia , Infecções Oculares Fúngicas/patologia , Feminino , Fungos/isolamento & purificação , Fusarium/isolamento & purificação , Humanos , Ceratite/tratamento farmacológico , Ceratite/patologia , Masculino , Pessoa de Meia-Idade , Natamicina/uso terapêutico , Estudos Retrospectivos , Fatores de Risco , Resultado do Tratamento , Voriconazol/uso terapêutico , Adulto Jovem
6.
Community Pract ; 85(3): 30-3, 2012 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-22479802

RESUMO

The changes that young people experience during early adolescence increase the risk that they may not reach their full potential. Poor parenting skills and an adverse family environment exacerbate existing behavioural problems and often result in academic failure. There is an expanding body of research supporting the important role of parents, family and community in determining young people's academic success in school. Parent and family-mediated interventions that target parenting skills have been shown across multiple intervention studies to be the most effective for reducing risk behaviour and preventing the development of later problem behaviour in adolescence. This article reports on the implementation of one such family intervention -the SFP10-14 (UK)- in a school in the north of England. It suggests a number of ways that practitioners working in the community can engage with families through family-mediated interventions to promote academic success in early adolescence.


Assuntos
Saúde da Família , Promoção da Saúde/organização & administração , Serviços de Saúde Mental/organização & administração , Adolescente , Atitude Frente a Saúde , Criança , Inglaterra , Feminino , Humanos , Masculino , Relações Pais-Filho , Pais/educação , Pais/psicologia , Psicologia do Adolescente , Instituições Acadêmicas
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