RESUMO
A 9-year-old female neutered collie-cross dog was presented with a 2-month history of persistent diarrhoea, weight loss and intermittent vomiting. Abdominal ultrasonography revealed one loop of jejunum with a markedly thickened and multifocally hyperechoic wall, without loss of wall layering. Laparotomies were performed for biopsy and resection of affected intestine. Histopathological examination revealed small intestinal ganglioneuromatosis (GN). The dog recovered well from surgery and the diarrhoea resolved. Eleven months later the dog has gained weight and remains asymptomatic. This is the first report of small intestinal GN affecting a mature dog, in which pathology was localized to the mucosal lamina propria and surgical treatment resulted in a successful outcome.
Assuntos
Diarreia/veterinária , Neoplasias do Sistema Digestório/veterinária , Doenças do Cão/patologia , Ganglioneuroma/veterinária , Jejuno/patologia , Neoplasia Endócrina Múltipla Tipo 2b/veterinária , Animais , Diarreia/diagnóstico por imagem , Diarreia/patologia , Diarreia/cirurgia , Neoplasias do Sistema Digestório/diagnóstico por imagem , Neoplasias do Sistema Digestório/patologia , Neoplasias do Sistema Digestório/cirurgia , Doenças do Cão/diagnóstico por imagem , Doenças do Cão/cirurgia , Cães , Feminino , Ganglioneuroma/diagnóstico por imagem , Ganglioneuroma/patologia , Ganglioneuroma/cirurgia , Jejuno/diagnóstico por imagem , Jejuno/cirurgia , Laparotomia , Neoplasia Endócrina Múltipla Tipo 2b/diagnóstico por imagem , Neoplasia Endócrina Múltipla Tipo 2b/patologia , Neoplasia Endócrina Múltipla Tipo 2b/cirurgia , Resultado do Tratamento , UltrassonografiaRESUMO
Renal dysplasia and nephrosclerosis in six calves, which were aged three to six months and from different farms in western Scotland and north-west England, was characterised clinically by stunted growth and renal failure with uraemia. Affected animals were depressed and one case exhibited severe neurological signs. Reduced erythrocyte counts were evident in three of four animals from which blood samples were submitted for haematology. At postmortem examination, the kidneys were bilaterally small, pale and firm, with marked fibrosis and sometimes contraction of the capsule. Histologically, affected calves had disorganised atrophic glomeruli, dilatation of tubules, loss of nephrons, areas of undifferentiated mesenchyme and diffuse interstitial and periglomerular fibrosis. There was minimal inflammation. Renal dysplasia and nephrosclerosis is a form of juvenile nephropathy of unknown aetiology that occurs sporadically in calves in the UK.
Assuntos
Doenças dos Bovinos/patologia , Nefropatias/veterinária , Falência Renal Crônica/veterinária , Nefroesclerose/veterinária , Uremia/veterinária , Animais , Animais Recém-Nascidos , Bovinos , Doenças dos Bovinos/congênito , Evolução Fatal , Feminino , Fibrose/congênito , Fibrose/patologia , Fibrose/veterinária , Transtornos do Crescimento/congênito , Transtornos do Crescimento/etiologia , Transtornos do Crescimento/patologia , Transtornos do Crescimento/veterinária , Rim/patologia , Nefropatias/congênito , Nefropatias/patologia , Falência Renal Crônica/congênito , Falência Renal Crônica/etiologia , Falência Renal Crônica/patologia , Masculino , Nefroesclerose/congênito , Nefroesclerose/patologia , Estudos Retrospectivos , Uremia/congênito , Uremia/etiologia , Uremia/patologiaRESUMO
Primary brain tumours were identified in two Bactrian camels (Camelus bactrianus) living at the Zoological Society of London's two zoos. Histology and immunohistochemistry were used to diagnose a histiocytic sarcoma in a 16-year-old female and a fibroblastic meningioma in a 13-year-old male. Before one died and the other was euthanased both camels had shown progressive neurological signs, including circling and ataxia.
