Attention-Deficit Hyperactivity Disorder Status Moderates Polysubstance Use Among Substance Using Populations: A Cross-Sectional Analysis.

INTRODUCTION: Attention-deficit hyperactivity disorder (ADHD) increases the risk for comorbid psychiatric and substance use disorders, which may increase the risk of adverse patient outcomes. This study examined the prevalence of ADHD in residential addiction treatment as well as the prevalence of mono-substance use, comorbid substance use, and polysubstance use disorders (PUD) as a function of ADHD status. METHODS: All participants were adults (18 years and older) admitted to a residential substance use disorder treatment center in Sioux Falls, SD. Participants were administered a Wender Utah ADHD rating scale to assess ADHD status using a cutoff score of 46. The participants were administered ADHD questionnaires developed to assess ADHD history, family history, and academic performance. RESULTS: Students showed a 17% increase in confidence in discussing substance use with patients and a 47% increase in confidence in applying MI techniques after the instructional session. At CC, 54.5% of patients reported substance use and 16.7% of those patients responded that they would consider quitting in the next month after the student interview. In the post-clinic survey, students rated an average of 4.21 out of 5 on comfort level in discussing excessive substance use. CONCLUSION: ADHD and substance use disorder have notable comorbidity. This study demonstrates a high prevalence of ADHD in populations with substance use disorder. The presence of ADHD may be a risk factor for PUD. Effective screening and treatment of ADHD may alleviate substance use burden among users.

Substance Use Disorder in Adults with ADHD in South Dakota.

INTRODUCTION: Attention-deficit hyperactivity disorder (ADHD) increases the risk for multiple comorbid psychiatric disorders, such as substance use disorder. Comorbid ADHD and substance use disorder has been shown to increase the risk of adverse occupational, social, psychological, and physical outcomes. Because of the severe risks of substance use, it is useful to determine the relative comorbidity of ADHD among different types of substance use disorders. This study examined the prevalence of ADHD in residential addiction treatment as well as the relative prevalence of ADHD among mono-substance use, comorbid substance use (2 comorbid substance use disorders), and polysubstance use (3+ substance use disorders). METHODS: Participants were adults admitted to residential treatment of substance use disorder. Participants were asked to complete a Wender Utah ADHD rating scale to assess the presence of ADHD. A cutoff score of 46 was used to determine presence of ADHD in this rating assessment. Participants were also provided with an ADHD history questionnaire designed for this study to gather information on childhood ADHD diagnoses, substance use history, and early-life effects o f attention disorders. RESULTS: Using the Wender Utah assessment scores, 55 participants with substance use disorder demonstrated an ADHD prevalence of 45% (n=30). Of the study population, 20% (n=11) of participants being diagnosed in childhood and another 25% (n=14) having a positive Wender Utah questionnaire score for ADHD as adult patients without a childhood diagnosis. All participants who had a childhood diagnosis of ADHD had received treatment for this disorder. Polysubstance use disorder (n=21) had an ADHD prevalence of 62%. Alcohol use disorder (n=21) had an ADHD prevalence of 24%. Methamphetamine use disorder (n=4) had an ADHD prevalence of 75%. Participants with ADHD (either during childhood or adulthood) had a nearly significant increase in the prevalence of polysubstance use disorder as compared to participants without ADHD (p = 0.0542). CONCLUSIONS: ADHD and substance use disorder have notable comorbidity. This study, among similar studies, demonstrates a high prevalence of ADHD in populations with substance use disorder. The presence of ADHD in patients with substance use disorder may influence which substances those patients choose to use. The difference in patients treated for childhood ADHD and those having a diagnosis of ADHD demonstrates a deficit in effective childhood ADHD screening. As such, effective screening and prevention of substance use disorder in patients with ADHD may be a useful tool in reducing the risk of developing substance use disorder. Additionally, adequate treatment of ADHD could be considered useful in treating a contributing element of substance use disorder.

Control of Nematodirus spp. infection by sheep flock owners in Northern Ireland.

BACKGROUND: To address a lack of information on the control of ovine helminth parasites in Northern Ireland (NI), a number of research projects have been undertaken, dealing with gastrointestinal nematodes, tapeworms and liver fluke. This investigation concerns Nematodirus and concentrates on three aspects of disease: farm management strategies for its control, derived from the results of a Questionnaire; the efficacy of treatment used by farmers, as determined by a coprological survey; and the hatching requirements of Nematodirus eggs, that is, whether prolonged chilling is a pre-requisite for hatching. RESULTS: A Questionnaire was sent to 252 sheep farmers in NI in March 2012 (covering the years 2009-2012) and replies were received from 228 farmers. Under-dosing, inaccurate calibration of equipment and inappropriate product choice were poor practices identified. Following this survey, the efficacy of treatment of Nematodirus spp. in sheep flocks was evaluated in April and May 2012. Sampling kits were sent to 51 flock owners, all of whom returned pre- and post-anthelmintic dosing faecal samples to the laboratory for analysis. At the time of treatment, 41 flocks were positive for Nematodirus (as diagnosed by the presence of eggs). Reduced benzimidazole efficacy was detected in 35.7% of flocks tested (n = 28). Although only involving a small number of flocks, reduced efficacy of levamisole treatment was detected in 50%, of avermectins in 33% and of moxidectin in 75% of flocks tested (n = 2, 6 and 4, respectively). In the egg hatch experiment, carried out under "chilled" and "non-chilled" conditions, 43% of the eggs in the "non-chilled" group were able to hatch, compared to 100% in the "chilled" group. CONCLUSIONS: The identification of inefficient control strategies argues for continued education of stockholders, in order to improve their management programmes. This is particularly important where the practices might impact on the development of anthelmintic resistance, which has been shown to exist on NI farms. The appropriate choice of anthelmintic is a vital part of this plan. The ability of eggs to hatch under non-chilled conditions demonstrates a flexibility in hatching behaviour. This may represent an adaptation to climate change and account for the recent emergence of a second, autumnal peak of infection.