Prevalence of major mental retardation and associated disabilities in the Canadian Maritime Provinces.

A cross-sectional survey of the prevalence of major mental retardation in 7- to 10-year-olds in the three Canadian Maritime provinces was carried out in 1980. Case ascertainment from multiple sources was considered to be virtually complete and resulted in a study group of 307 children, for whom 72% of the parents consented to personal data collection. The overall regional prevalence of major mental retardation was 3.65/1,000. Variation in county prevalence rate (based on parental residence at the time of birth) was associated, by regression analysis, with maternal age, areas of greater population concentrations, and number of physicians per capita. These associations were still present when children with Down syndrome were excluded from the analysis. Speech and behavior disorders and epilepsy were the major associated disabilities.

Causal origins of major mental handicap in the Canadian Maritime provinces.

From a retrospective epidemiological survey, the prevalence of major mental handicap among seven- to 10-year-old children in the Maritime region of Canada in 1980 was estimated to be 36.5 per 10,000 children. Based on information obtained for 221 of the 307 children ascertained by the survey, prenatal origins dominated (58 per cent), followed by perinatal (10 per cent) and postnatal (4 per cent). No specific cause could be determined for 27 per cent of the children, but 41 per cent of this group had epilepsy and/or cerebral palsy in addition to major mental handicap. Significant differences were found in the causal spectrum between the Maritime region of Canada and regions studied in other developed countries. The results of this survey have implications for planning prevention programs, and for epidemiological surveillance and monitoring of adverse reproductive outcomes.