1.
J Toxicol Environ Health
; 29(4): 399-407, 1990.
Artigo
em Inglês
| MEDLINE
| ID: mdl-2325153
RESUMO
Pellets of crude shale oil, neutral, basic, or polynuclear aromatic fractions of shale oil, or crude petroleum were implanted in the lungs of rats through a thoracotomy. The pellets had a beeswax-tricaprylin vehicle that allowed the slow release of material into the surrounding parenchyma. A dose-related incidence of lung cancer was observed with each of the materials studies. A greater risk for lung cancer was not demonstrated for crude shale oil compared to crude petroleum.
Assuntos
Carcinoma de Células Escamosas/induzido quimicamente , Neoplasias Pulmonares/induzido quimicamente , Petróleo/efeitos adversos , Animais , Carcinoma de Células Escamosas/patologia , Implantes de Medicamento , Feminino , Neoplasias Pulmonares/patologia , Ratos , Ratos Endogâmicos
2.
Health Phys
; 44(3): 275-7, 1983 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-6832980