RESUMO
The effects on lung function of labetalol (a combined alpha and beta adrenergic receptor blocker) and three beta adrenergic receptor blockers (propranolol, atenolol, metoprolol) have been assessed in patients with chronic airflow obstruction using a double-blind trial. With the dosages used, all drugs produced an equivalent fall of blood pressure. Propranolol was the only drug that significantly increased airways obstruction (FEV1, specific airways resistance). Following salbutamol, labetalol was associated with a significantly greater improvement of airflow than either propranolol or metoprolol. On these acute studies, the order of preference for beta blocking drugs in management of hypertension in patients with obstructive airways disease, would be labetalol, (atenolol) or (metoprolol) and then propranolol.
Assuntos
Antagonistas Adrenérgicos beta/efeitos adversos , Etanolaminas/efeitos adversos , Hipertensão/tratamento farmacológico , Labetalol/efeitos adversos , Pneumopatias Obstrutivas/induzido quimicamente , Antagonistas Adrenérgicos beta/uso terapêutico , Idoso , Atenolol/efeitos adversos , Humanos , Labetalol/uso terapêutico , Medidas de Volume Pulmonar , Metoprolol/efeitos adversos , Pessoa de Meia-Idade , Propranolol/efeitos adversosRESUMO
Unilateral hydrothorax occurring during peritoneal dialysis is well described and has been presumed to be secondary to a pleuroperitoneal communication. Diagnosis of these communications usually requires invasive procedures. A non-invasive method of confirmation of abnormal pleuro-peritoneal communication using radionuclide scanning is outlined. The occurrence of this complication has usually meant cessation of this type of dialysis. However, this patient illustrates that continuation of peritoneal dialysis is possible.
