Utility of a Short Neuropsychological Protocol for Detecting HIV-Associated Neurocognitive Disorders in Patients with Asymptomatic HIV-1 Infection.

Human Immunodeficiency Virus type 1 (HIV-1) infection is a chronic disease that affects ~40 million people worldwide. HIV-associated neurocognitive disorders (HAND) are common in individuals with HIV-1 Infection, and represent a recent public health problem. Here we evaluate the performance of a recently proposed short protocol for detecting HAND by studying 60 individuals with HIV-1-Infection and 60 seronegative controls from a Caribbean community in Barranquilla, Colombia. The short evaluation protocol used significant neuropsychological tests from a previous study of asymptomatic HIV-1 infected patients and a group of seronegative controls. Brief screening instruments, i.e., the Mini-mental State Examination (MMSE) and the International HIV Dementia Scale (IHDS), were also applied. Using machine-learning techniques, we derived predictive models of HAND status, and evaluated their performance with the ROC curves. The proposed short protocol performs exceptionally well yielding sensitivity, specificity, and overall prediction values >90%, and better predictive capacity than that of the MMSE and IHDS. Community-specific cut-off values for HAND diagnosis, based on the MMSE and IHDS, make this protocol suitable for HAND screening in individuals from this Caribbean community. This study shows the effectivity of a recently proposed short protocol to detect HAND in individuals with asymptomatic HIV-1-Infection. The application of community-specific cut-off values for HAND diagnosis in the clinical setting may improve HAND screening accuracy and facilitate patients' treatment and follow-up. Further studies are needed to assess the performance of this protocol in other Latin American populations.

Assessing the measurement invariance of a Latin-American Spanish translation of the Body Appreciation Scale-2 in Mexican, Argentinean, and Colombian adolescents.

In order to advance in the study of positive body image among different cultures, it is important to create culturally appropriate measures. We examined the psychometric properties of a Latin-American Spanish translation of the Body Appreciation Scale-2 (BAS-2; Tylka & Wood-Barcalow, 2015a), specifically assessing measurement invariance using a large sample of 3845 male and female adolescents from Argentina, Mexico, and Colombia. Participants completed the BAS-2, Eating Disorder Inventory-2, Male Body Attitude Scale and the Sociocultural Attitudes Toward Appearance Questionnaire-3. The BAS-2 had a unidimensional factor structure in each of the three samples. We confirmed the structural, metric, and scalar invariance of the scale regardless of gender or country. Adolescents in Argentina had lower body appreciation compared with those in Mexico and Colombia. Overall, females had lower body appreciation than males, with the greatest gender difference found in the Argentinean sample. Our findings strongly support the validity and reliability of this Latin-American translation of the BAS-2 in measuring positive body image in adolescents in Argentina, Mexico, and Colombia.