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J Neurol Sci ; 383: 214-215, 2017 Dec 15.
Artigo em Inglês | MEDLINE | ID: mdl-29108750

RESUMO

Zika virus infection represents a new neuropathological agent with association to a wide spectrum of neurological complications: a) Congenital Zika Syndrome by affecting the neural stem cells of the human fetal brain; b) Guillain-Barré Syndrome by an autoimmune response against peripheral myelin and/or axonal components or probable direct inflammatory reaction; c) Encephalitis/meningoencephalitis and myelitis by a direct viral inflammatory process on the central nervous system; d) Sensory neuropathy by infecting directly the peripheral neurons and causing substantial cell death and pathogenic transcriptional dysregulation; e) Acute Disseminated Encephalomyelitis and optic neuropathy; f) Seizures and Epilepsy and g) childhood arterial ischemic stroke by probable inflammatory reaction and endothelial injury.


Assuntos
Doenças do Sistema Nervoso/etiologia , Infecção por Zika virus/complicações , Humanos , Doenças do Sistema Nervoso/fisiopatologia , Infecção por Zika virus/fisiopatologia
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