[Metabolic changes during hyperbaric oxygenation]. / Izmenenie obmena veshchestv pri giperbaricheskoi oksigenatsii.

Biochemical changes in response to a high partial pressure of oxygen were investigated in 12 test subjects. During exposure to compressed oxygen breathing (pO2-0.25 MPa) for a limited period of time changes in the carbohydrate, protein, enzyme, and electrolyte status were seen. These changes were demonstrative sings of physiological and toxic effects of oxygen. Individual metabolic responses were investigated and optimal exposure times were determined. It is recommended to take into consideration biochemical variations when identifying human resistance to oxygen toxicity on an individual basis.

[Predicting the genome response of the somatic cells of divers to hyperoxic medium]. / Prognozirovanie reaktsii genoma somaticheskikh kletok vodolazov na giperoksicheskuiu sredu.

Cytogenetical consequences of high oxygen pressure action (HOB) have been studied in professional and nonprofessional divers after deepening. Blood samples of subject from both groups were treated with HBO in vitro to compare individual reaction of the somatic cells genome to HOB. The present study reveals that HBO increases the level of chromosome aberrations, and individual response to HBO differs. There is a correlation between the level of chromosome aberrations in vivo and in vitro. This indicates that blood treatment in vitro can reveal the sensitivity of the genome in human before HBO treatment. According to the data in vitro 2 groups of the genome response to HBO: up to 20% and higher than 20% aberrations are distinguished.