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Epidemiol Infect ; 148: e257, 2020 10 23.
Artigo em Inglês | MEDLINE | ID: mdl-33092672

RESUMO

The outbreak of the novel coronavirus severe acute respiratory syndrome-coronavirus-2 has raised major health policy questions and dilemmas. Whilst respiratory droplets are believed to be the dominant transmission mechanisms, indirect transmission may also occur through shared contact of contaminated common objects that is not directly curtailed by a lockdown. The conditions under which contaminated common objects may lead to significant spread of coronavirus disease 2019 during lockdown and its easing is examined using the susceptible-exposed-infectious-removed model with a fomite term added. Modelling the weekly death rate in the UK, a maximum-likelihood analysis finds a statistically significant fomite contribution, with 0.009 ± 0.001 (95% CI) infection-inducing fomites introduced into the environment per day per infectious person. Post-lockdown, comparison with the prediction of a corresponding counterfactual model with no fomite transmission suggests fomites, through enhancing the overall transmission rate, may have contributed to as much as 25% of the deaths following lockdown. It is suggested that adding a fomite term to more complex simulations may assist in the understanding of the spread of the illness and in making policy decisions to control it.


Assuntos
Betacoronavirus , Infecções por Coronavirus/mortalidade , Infecções por Coronavirus/transmissão , Fômites/virologia , Pneumonia Viral/mortalidade , Pneumonia Viral/transmissão , Fatores Etários , Betacoronavirus/isolamento & purificação , COVID-19 , Infecções por Coronavirus/prevenção & controle , Política de Saúde/tendências , Humanos , Incidência , Funções Verossimilhança , Modelos Teóricos , Pandemias/prevenção & controle , Pneumonia Viral/prevenção & controle , Serviços Postais/estatística & dados numéricos , SARS-CoV-2 , Reino Unido/epidemiologia
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