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1.
Lupus ; 33(8): 886-891, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38719778

RESUMO

In rare instances, patients with SLE may exhibit atypical clinical manifestations, such as Hypocomplementemic Urticarial Vasculitis, which can pose diagnostic challenges. Here, we present a case report of a 28-year-old female with a history of SLE with lupus nephritis clase IV who developed HUV-like symptoms, ultimately leading to a diagnosis of C1q Vasculitis. This case underscores the importance of considering C1q Vasculitis in SLE patients presenting with HUV-like features and highlights Rituximab as a promising therapeutic option for managing this rare condition.


Assuntos
Complemento C1q , Lúpus Eritematoso Sistêmico , Rituximab , Urticária , Vasculite , Humanos , Feminino , Adulto , Complemento C1q/deficiência , Lúpus Eritematoso Sistêmico/complicações , Lúpus Eritematoso Sistêmico/diagnóstico , Vasculite/diagnóstico , Vasculite/tratamento farmacológico , Urticária/diagnóstico , Rituximab/uso terapêutico , Nefrite Lúpica/diagnóstico , Nefrite Lúpica/complicações , Nefrite Lúpica/tratamento farmacológico , Diagnóstico Diferencial
2.
Skinmed ; 19(4): 310-312, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34526209

RESUMO

A 40-year-old woman with a family history of gastric, pulmonary, and endometrial cancers (parents and grandparents) was referred to our institution with a 3-year history of progressive pruritus with palmar and plantar papules. On physical examination, there were keratotic yellowish pinpoint papules on the hands (Figure 1) and yellowish keratotic plaques and papules on the plantar pressure points (Figure 2). The diagnosis of punctate palmoplantar keratoderma was confirmed histopathologically (Figure 3), and treatment was initiated with 30% urea cream, which proved helpful. Molecular studies were requested, which documented a variant in the AAGAB gene. After treatment, the patient slightly improved and clinical symptoms were better tolerated.


Assuntos
Ceratodermia Palmar e Plantar , Verrugas , Proteínas Adaptadoras de Transporte Vesicular , Adulto , Feminino , Mãos , Humanos , Ceratodermia Palmar e Plantar/diagnóstico , Ceratolíticos , Verrugas/diagnóstico
3.
Dermatol Online J ; 26(10)2020 Oct 15.
Artigo em Inglês | MEDLINE | ID: mdl-33147676

RESUMO

Pemphigus vegetans is a rare variant of pemphigus vulgaris, characterized by vegetative lesions that develop mainly in flexural areas. Herein, we present a middle-aged woman who presented to the emergency department with a rare cutaneous finding of bilateral axillary pustules that progressed over months to vegetant and malodorous plaques associated with subsequent painful erosions.


Assuntos
Glucocorticoides/uso terapêutico , Pênfigo/patologia , Prednisona/uso terapêutico , Adulto , Axila/patologia , Diagnóstico Diferencial , Feminino , Humanos , Mucosa Bucal/patologia , Pênfigo/diagnóstico , Pênfigo/tratamento farmacológico
4.
Univ. med ; 52(1): 100-104, ene.-mar. 2011. ilus
Artigo em Espanhol | LILACS | ID: lil-620373

RESUMO

El lupus vulgar es una de las formas más frecuentes de tuberculosis cutánea. Se trata de una forma crónica y benigna que se presenta en pacientes previamente sensibilizados a Mycobacterium tuberculosis y su diagnóstico se basa principalmente en los hallazgos clínicos e histopatológicos. Se presenta el caso de un paciente de 48 años con antecedentes de infección por virus de inmunodeficiencia humana (VIH), que desarrolló lupus vulgar en el codo derecho, de un año de evolución...


Lupus vulgaris is one of the most common forms of cutaneous tuberculosis. It is a chronic and benign form that usually occurs in patients that had been previously sensitized to Mycobacterium tuberculosis and its diagnosis is based mainly in the clinical and histopathological findings. We present the case of a 48 year old male with HIV infection, who developed lupus vulgaris on his right elbow over a one year period...


Assuntos
Lúpus Eritematoso Cutâneo , Lúpus Eritematoso Sistêmico
5.
Univ. med ; 45(1): 13-16, ene.-mar. 2004. ilus, tab
Artigo em Espanhol | LILACS | ID: lil-501120

RESUMO

Los carcinomas de glándula mamaria se han convertido en la lesión tumoral maligna más frecuente en las mujeres de los países desarrollados. En nuestro medio también es una patología de alta incidencia y prevalencia, sólo superada por las lesiones neoplásicas y preneoplásicas del cuello uterino. El manejo y el pronóstico de estas pacientes están ligados a las características histológicas de la lesión y al estado de los ganglios linfáticos axilares. Gracias al tamizaje mamográfico es posible detectar lesiones muy pequeñas, no palpables, en las cuales es casi nulo el riesgo de enfermedad metastásica; en estos casos, se logra una supervivencia libre de enfermedad a los 10 años mayor del 90%. Con el presente trabajo pretendemos mostrar la situación de nuestro hospital frente a esta patología.


Assuntos
Humanos , Carcinoma , Glândulas Mamárias Humanas , Tumor Misto Maligno
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