1.
J Antibiot (Tokyo)
; 48(3): 254-60, 1995 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-7730161
RESUMO
The synthesis and a conformational study of a number of homologues of the well known antibiotic, phytotoxic leucinostatin A are reported. The circular dichroism of all the compounds are discussed. Some conclusions on the SAR of these compounds are drawn. The influence of the alpha-helical conformation and/or the increased lipophile character on their interesting biological activities is emphasized.