[Solid pseudopapillary neoplasm. Report of three cases and review of the literature]. / Neoplasia sólida pseudopapilar. Reporte de tres casos y revisión de la literatura.

Background: Solid pseudopapillary neoplasm, or Frantz-Gruber tumor, is a diagnostic challenge for the surgical pathologist. It is classified by the WHO as a malignant epithelial tumor of the pancreas, its prevalence is low, it occurs in only 1 to 2% of all malignant tumors of the pancreas, it usually affects mainly young women, its origin is still unclear, it is generally It presents as a solitary, encapsulated lesion, without invasion of peripancreatic tissues with rare cases of metastasis, which is why it is considered a low-grade malignant tumor by the WHO. The objective of this article is to present three clinical cases and to evaluate the epidemiology, clinical manifestations, morphology and immunohistochemical expression of the tumor in a review of the bibliography, as well as to compare it with the cases already reported on the subject. Clinical case: Three cases of Frantz tumor were diagnosed by the pathology department of a tertiary hospital are presented, which correspond to two women aged 17 and 34, as well as a 52-year-old man whose presentation by age and sex is rare. Conclusions: After the bibliographical review and the analysis of the cases presented, we verified the difficulty to make a correct diagnosis, since its presence is rare in the daily practice of the surgical pathologist. The morphological patterns of the solid pseudopapillary tumor are varied and can often be reminiscent of neuroendocrine tumors of the pancreas, whose presentation rate is higher.

Evaluación forense comparativa del método odontológico de Carrea para estimar la talla real en cadáveres mexicanos / Forensic comparative evaluation of the dental method of Carrea to estimate real height in Mexican corpses

Objetivo. Determinar la efectividad del método odontológico de Carrea para estimar la talla real de cadáveres mexicanos. Material y métodos. Estudio analítico, correlacional y transversal en 2 poblaciones mexicanas cadavéricas. Muestra: 56 cadáveres, 32 de Veracruz y 24 del Distrito Federal. En cada cadáver se realizaron 4 mediciones morfométricas, de las cuales se obtuvieron 5 derivadas. Análisis estadístico: 1) se calcularon media y desviación estándar (DE); 2) para sexo, se utilizaron las pruebas t Student y de Levene para comparación de medias y DE; 3) para calcular la variabilidad entre muestras, se realizó un análisis de componentes principales; 4) las tallas real, mínima, máxima y promedio se compararon mediante un ANOVA unifactorial y 5) se realizó un análisis de correlación de Pearson entre las tallas real y mínima. Resultados. No se encontraron diferencias entre las 2 muestras de cadáveres estudiadas ni entre las tallas real y mínima en ninguno de los 2 grupos: Distrito Federal, talla real (172,08 ± 6,53 cm) y talla mínima (171,35 ± 7,81 cm) (p > 0,05); Veracruz, talla real (167,5 ± 5,77 cm) y talla mínima (166,50 ± 6,36 cm) (p > 0,05). Se obtuvo que la correlación entre la talla real y la mínima es adecuada tanto para la muestra del Distrito Federal (r = 0,79; p = 0,000) como para la de Veracruz (r = 0,82; p = 0,000), así como en conjunto (r = 0,83; p = 0,000). Conclusiones. El método odontológico de Carrea, utilizando la talla mínima como referencia, es un excelente estimador de la talla real en cadáveres mexicanos (AU)

Objective. Evaluate the usefulness of the dental method of Carrea to estimate the height in Mexican population. Material and methods. Analytical, correlational and cross-sectional study in 2 cadaveric Mexican populations. Sample: 56 bodies, 32 of Veracruz and 24 of the Federal District. In each corpse 4 morphometric measurements were performed, of which 5 derivatives were obtained. Statistical analysis: 1) mean and standard deviation (SD) was calculated; 2) for sex, t Student and Levene tests for comparison of means and SDs were used; 3) to calculate the variability between Federal District and Veracruz, principal component analysis was made; 4) the heights, real, minimum, average and maximum were compared by univariate ANOVA, and 5) a Pearson correlation analysis between actual and minimum heights was performed. Results. No differences were found between the 2 cadavers samples studied, neither between real and minimum height in either group: Federal District, real height (172.08 ± 6.53 cm.) and minimum height (171.35 ± 7.81 cm) (P>.05); Veracruz, real height (167.5 ± 5.77 cm) and minimum height (166.50 ± 6.36 cm) (P>.05), having that the correlation between real height and the minimum height is advisable for both samples, Federal District (r=.79, P=.000), Veracruz (r=.82, P=.000) and overall (r=.83, P=.000). Conclusions. The dental Carrea's method, using the minimum height reference, is an excellent estimate of the actual size in mexican corpses (AU)

An educational strategy for improving knowledge about breast and cervical cancer prevention among Mexican middle school students.

INTRODUCTION: Prevention programs have not achieved the expected results in preventing mortality from breast and cervical cancer in Mexico. Therefore, we propose a complementary strategy. METHODOLOGY: An educational strategy for high school students in Mexico (2011-2013) was designed (longitudinal design, two measurements and a single intervention). The postintervention assessment included: 1) knowledge acquired by students about cancer prevention and 2) The performance of the student as a health promoter in their household. The strategy was based on analysis of cases and developed in three sessions. An assessment tool was designed and validated (Test-Retest). The levels of knowledge according to the qualifications expected by chance were determined. Wilcoxon test compared results before and after intervention. RESULTS: An assessment instrument with 0.80 reliability was obtained. 831 high school students were analyzed. Wilcoxon rank-sum test showed a significant learning after the intervention (Z = - 2.64, p = 0.008) with improvement of levels of knowledge in a 154.5%. 49% of students had a good performance as health promoters. CONCLUSIONS: The learning in preventive measures is important to sensitize individuals to prevention campaigns against cancer. This strategy proved to improve the level of knowledge of students in an easy and affordable way.

Effect of dietary intake of avocado oil and olive oil on biochemical markers of liver function in sucrose-fed rats.

Metabolic changes, along with cardiovascular and hepatic factors, are associated with the development of diseases such as diabetes, dyslipidemia, and obesity. We evaluated the effect of avocado oil supplementation (centrifuged and solvent extracted), compared with olive oil, upon the hepatic function in sucrose-fed rats. Twenty-five rats were divided into five groups: control (basal diet), a sucrose-fed group (basal diet plus 30% sucrose solution), and three other groups (S-OO, S-AOC, and S-AOS, indicating basal diet plus 30% sucrose solution plus olive oil OO, avocado oil extracted by centrifugation AOC or using solvent AOS, resp.). Glucose, total cholesterol, triglycerides, total protein, albumin, globulin, direct bilirubin, glutamic pyruvic transaminase, glutamic oxaloacetic transaminase, alkaline phosphatase, cholinesterase, and α -amylase concentrations were determined and avocado oil effect on them was studied. In some cases the induced metabolic alteration significantly affected total protein and bilirubin levels and also had a highly significant effect on α -amylase levels. AOC and AOS exhibited effects similar to those of olive oil, according to the nonsignificant difference in fatty acid profile observed by other authors. Avocado oil consumption could be beneficial in the control of altered metabolic profile illnesses as it presents effects on hepatic function biochemical markers similar to olive oil.

Avocado oil supplementation modifies cardiovascular risk profile markers in a rat model of sucrose-induced metabolic changes.

The purpose of this study was to evaluate the effects of avocado oil administration on biochemical markers of cardiovascular risk profile in rats with metabolic changes induced by sucrose ingestion. Twenty-five rats were divided into five groups: a control group (CG; basic diet), a sick group (MC; basic diet plus 30% sucrose solution), and three other groups (MCao, MCac, and MCas; basic diet plus 30% sucrose solution plus olive oil and avocado oil extracted by centrifugation or using solvent, resp.). Glucose, total cholesterol, triglycerides, phospholipids, low- and high-density lipoproteins (LDL, HDL), very low-density lipoprotein (VLDL), lactic dehydrogenase, creatine kinase, and high sensitivity C-reactive protein concentration were analyzed. Avocado oil reduces TG, VLDL, and LDL levels, in the LDL case significantly so, without affecting HDL levels. An effect was exhibited by avocado oil similar to olive oil, with no significant difference between avocado oil extracted either by centrifugation or solvent in myocardial injury biochemical indicators. Avocado oil decreased hs-CRP levels, indicating that inflammatory processes were partially reversed. These findings suggested that avocado oil supplementation has a positive health outcome because it reduces inflammatory events and produces positive changes in the biochemical indicators studied, related to the development of metabolic syndrome.

Biopsia por aspiración con aguja fina en la enfermedad neoplásica de higado: experiencia de cinco años / Fine needle aspiration buopsy in liver neoplasms: a five years experience

En un análisis retrospectivo de cinco años en el Servicio de Citología del Departamento de Patología del Hospital de Oncología del Centro Médico Nacional "Siglo XXI", IMSS, se encontraron 123 biopsias de hígado por aspiración con aguja fina. En 60 de ellas hubo, además, biopsia con aguja tipo tru-cut lo que permitió establecer una correlación citohistopatológica para determinar la sensibilidad y especificidad del método. Estos 60 casos constituyen la base de datos para este análisis. En 25 de los casos el diagnóstico citológico fue de benignidad y en 24 se confirmó; sólo hubo un falso negativo. En los otros 35 casos hubo evidencia citológica de malignidad, en 30 de los cuales se confirmo por truc-cut; sólo hubo falsos positivos y los otros casos fueron innegablemente malignos por citología, no obstante, la biopsia no mostró la neoplasia. El análisis estadístico de estos datos dio los siguientes resultados: sensibilidad 97.05 por ciento, especificidad 92.3 por ciento, valor predictivo positivo 94.2 por ciento y valor predictivo negativo 96 por ciento. Estas cifras son similares a las publicadas en otras series. Se concluye que la biopsia por aspiración con aguja fina de hígado es un procedimiento seguro, rápido, no costoso y confiable para detectar neoplasias hepáticas y diferenciarlas entre primarias y metastásicas