A review of international and developed practices of medical physics from a legislative and regulatory point of view and its applicability and comparison with Pakistan.

The importance of the medical physics profession and medical physicists is widely recognized by the international bodies like ILO, IAEA, EC, etc. The description of a medical physicist's qualification framework, their role and responsibilities have been addressed in the legislative and regulatory frameworks of developed countries like the USA (in 10CFR) and the EC (EC RP 174) and less comprehensively in developing counties like Pakistan. AFOMP has contributed positively in various regulatory and policy matters regarding the medical physics practices in Asian countries. Furthermore, the recommendations of IAEA's regional meeting on "Medical Physics in Europe-Current Status and Future Perspective" in Vienna, 2015, address the need and mechanism of a harmonized framework for medical physicists' qualifications. The lack of a comprehensive professional recognition framework becomes more challenging when we see that hi-tech diagnostic (e.g. PET CT) and therapeutic (e.g. cyberknife, VMAT, tomotherapy, etc.) modalities are now available in many parts of the world, including Pakistan which still have a basic level of medical physics qualification and practices. Therefore, international efforts like the above-mentioned IAEA-EC meeting in 2015; and by AFOMP activities related to training, qualification and recognition of medical physicists can provide a pathway to further improve medical physics practices in the developing world. The objective of this review is to (i) summarize the international practices for the legislation and regulation of medical physics, (ii) provide a brief overview of the medical physics practices in Pakistan and (iii) discuss the applicability of the IAEA-EC meeting's recommendations to the case of Pakistan. The review highlights the areas which are addressed in IAEA-EC meeting and could be beneficial to other nations as well, particularly, for low and middle income countries. The review also presents few suggestions how to progress with the medical physics profession in developing countries in general, and in Pakistan in particular. These suggestions also include further possible pathway the IAEA could consider, like IAEA project or meetings, to further strengthen the medical physics profession globally.

Radiofrequency radiations induced genotoxic and carcinogenic effects on chickpea (Cicer arietinum L.) root tip cells.

Present study was under taken to predict the possible DNA damages (genotoxicity) and carcinogenicity caused by radiofrequency radiations (RF) to living tissue. Dry seeds of chickpea were treated with GSM cell phone (900 MHz) and laptop (3.31 GHz) as RF source for 24 and 48 h. Untreated seeds were used as (0 h) negative control and Gamma rays (250 Gray) as positive control. Plant chromosomal aberration assay was used as genotoxicity marker. All the treatment of RF inhibits seed germination percentage. 48 h laptop treatment has the most negative effect as compared to untreated control. A decrease was observed in mitotic index (M.I) and increase in abnormality index (A.I) with the increase in exposure duration and frequency in (Hz). Cell membrane damages were also observed only in 48 h exposure of cell phone and laptop (RF). Maximum nuclear membrane damages and ghost cells were again recorded in 48 h exposure of cell phone and laptop. The radiofrequency radiations (900 MHz and 3.31 GHz) are only genotoxic as they induce micronuclei, bi-nuclei, multi-nuclei and scattered nuclei but could be carcinogenic as 48 h incubation of RF induced fragmentation and ghost cells. Therefore cell phones and laptop should not be used unnecessarily to avoid possible genotoxic and carcinogenic effects.

Dose measurement of cobalt-60 radiotherapy beams in treatment fields.

BACKGROUND: Radiation-therapy is a complex process with multiple steps, each of which has an impact on the quality of treatment. Accurate dosimetry is a critical step during the radiotherapy of cancer patients.The aim of the present study was to measure and evaluate the doses of two cobalt- 60 (60Co) teletherapy units GWXJ80 of NPIC China and Theratron 780 of AECL Canada at various points within fields for different field sizes. METHODS: This cross-sectional descriptive study was done to measure the 60Co doses in the treatment fields.The dose measurements were done in air and 30x30x30 cm3 Phantom at 80 cm SSD by using calibrated NE 2570 Farmer Electrometer & NE 2571 Farmer Ionization Chamber and percentage of doses were calculated. RESULTS: The results showed that 60% central area of all fields ranging from 100-98.79% and 100-96.12% for GWXJ80 in the air and phantom, whereas for Theratron 780, they were ranging from 100-98.50% and 100-96.45% in air and phantom respectively. The percentages of doses at the edges for GWXJ80 and Theratron 780 in the air were 75.39-38.66% & 85.65-46.47% respectively and they were 82.22-40.39% & 49.05-24.55% respectively in phantom. CONCLUSIONS: The doses within 60% central area of fields in air were higher than phantom for both teletherapy units. The doses at field edges in air were lower in GWXJ80 than Theratron 780 whereas in phantom they were vice versa. But all were in the acceptable range as recommended by International Commission on Radiation Units and Measurements.