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1.
Appl Radiat Isot ; 69(7): 1057-63, 2011 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-21454082

RESUMO

It is possible to apply the k(0)-method using a simplified equation for concentration calculations using Excel spreadsheet, using comparators without making corrections. The objective of this study was to confirm that the k(0)-standardization method is more efficient and accurate than this "k(0)-comparator" procedure, applying suitable software that takes into account several corrections. The reference material GBW07401 soil was analyzed in this study. Relative Bias and u-score tests were used in order to evaluate the overall results.

2.
Appl Radiat Isot ; 66(10): 1307-12, 2008 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-18455924

RESUMO

In this work, a comparative study of neutron activation analysis (NAA) was performed by the nuclear institutes: CDTN/CNEN-Brazil, CCHEN-Chile and the SCK.CEN-Belgium aiming to investigate some generic, manipulated and reference medicines largely commercialized in Brazil. Some impurities such as: As, Ba, Br, Ce, Co, Cr, Eu, Fe, Hf, Sb, Sc, Sm, Ti and Zn were found, and the heterogeneity of the samples pointed out the lack of an efficient public system of quality control.


Assuntos
Avaliação de Medicamentos/métodos , Avaliação de Medicamentos/normas , Medicamentos Genéricos/análise , Medicamentos Genéricos/normas , Análise de Ativação de Nêutrons/métodos , Análise de Ativação de Nêutrons/normas , Brasil , Valores de Referência
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