Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 3 de 3
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
2.
Quant Imaging Med Surg ; 6(1): 16-24, 2016 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-26981451

RESUMO

BACKGROUND: Lung cancer results in the highest number of cancer deaths worldwide. The segmentation of lung nodules is an important task in computer systems to help physicians differentiate malignant lesions from benign lesions. However, it has already been observed that this may be a difficult task, especially when nodules are connected to an anatomical structure. METHODS: This paper proposes a method to estimate the background of the nodule area and how this estimation is used to facilitate the segmentation task. RESULTS: Our experiments indicate more than 99% of accuracy with less than 1% of false positive rate (FPR). CONCLUSIONS: The proposed methods achieved better results than a state-of-the-art approach, indicating potential to be used in medical image processing systems.

3.
Org Lett ; 13(16): 4434-7, 2011 Aug 19.
Artigo em Inglês | MEDLINE | ID: mdl-21797204

RESUMO

Starting with commercial reagents, bicyclic 1,2,3-triazolium ionic liquids [b-3C-tr][NTf(2)] (1) and [b-4C-tr][NTf(2)] (2) were synthesized in four steps with high overall isolated yields of 68% and 76%, respectively. Since the C-5 hydrogen is acidic, under basic condition ionic liquids 1 and 2 were readily methylated with methyl iodide to afford chemically stable ionic liquids 7 and 8 at room temperature (88% and 82%, respectively). Ionic liquid 1 was used as the ionic solvent to demonstrate its usefulness for the synthesis of rutaecarpine, a natural product.


Assuntos
Compostos Bicíclicos Heterocíclicos com Pontes/química , Alcaloides Indólicos/síntese química , Líquidos Iônicos/química , Quinazolinas/síntese química , Triazóis/química , Alcaloides Indólicos/química , Estrutura Molecular , Quinazolinas/química
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...