Coupled disease-vaccination behavior dynamic analysis and its application in COVID-19 pandemic.

Predicting the evolutionary dynamics of the COVID-19 pandemic is a complex challenge. The complexity increases when the vaccination process dynamic is also considered. In addition, when applying a voluntary vaccination policy, the simultaneous behavioral evolution of individuals who decide whether and when to vaccinate must be included. In this paper, a coupled disease-vaccination behavior dynamic model is introduced to study the coevolution of individual vaccination strategies and infection spreading. We study disease transmission by a mean-field compartment model and introduce a non-linear infection rate that takes into account the simultaneity of interactions. Besides, the evolutionary game theory is used to investigate the contemporary evolution of vaccination strategies. Our findings suggest that sharing information with the entire population about the negative and positive consequences of infection and vaccination is beneficial as it boosts behaviors that can reduce the final epidemic size. Finally, we validate our transmission mechanism on real data from the COVID-19 pandemic in France.

Application of diffusion tensor imaging technology in glaucoma diagnosis.

Glaucoma is the first major category of irreversible blinding eye illnesses worldwide. Its leading cause is the death of retinal ganglion cells and their axons, which results in the loss of vision. Research indicates that glaucoma affects the optic nerve and the whole visual pathway. It also reveals that degenerative lesions caused by glaucoma can be found outside the visual pathway. Diffusion tensor imaging (DTI) is a magnetic resonance imaging (MRI) technique that can investigate the complete visual system, including alterations in the optic nerve, optic chiasm, optic tract, lateral geniculate nuclear, and optic radiation. In order to provide a more solid foundation for the degenerative characteristics of glaucoma, this paper will discuss the standard diagnostic techniques for glaucoma through a review of the literature, describe the use of DTI technology in glaucoma in humans and animal models, and introduce these techniques. With the advancement of DTI technology and its coupling with artificial intelligence, DTI represents a potential future for MRI technology in glaucoma research.

Analysis of epidemic vaccination strategies on heterogeneous networks: Based on SEIRV model and evolutionary game.

Nowadays, vaccination is the most effective way to control the epidemic spreading. In this paper, an epidemic SEIRV (susceptible-exposed-infected-removed -vaccinated) model and an evolutionary game model are established to analyze the difference between mandatory vaccination method and voluntary vaccination method on heterogeneous networks. Firstly, we divide the population into four categories, including susceptible individuals, exposed individuals, infected individuals and removed individuals. Based on the mean field approximation theory, differential equations are developed to characterize the changes of the proportions of the four groups over time under mandatory vaccination. Then through the analysis of the differential equations, the disease-free equilibrium point (DFE) and the endemic disease equilibrium point (EDE) are obtained. Also, the basic reproduction number is obtained by the next-generation matrix method and the stability analysis of the equilibrium points is performed. Next, by considering factors such as vaccination cost, treatment cost and government subsidy rate, differential equations are established to represent the change of vaccination rate over time. By analyzing the final vaccination coverage rate, we can get the minimum vaccination cost to make infectious disease disappear. Finally, the Monte Carlo method is used for numerical simulation to verify the results obtained from the theoretical analysis. Using the SARS-Cov-2 pandemic data from Wuhan, China, the experimental results show that when the effectiveness rate of vaccination is 0.75, the vaccination cost is not higher than 0.886 so that the vaccination strategy can be spread among the population. If mandatory vaccination is adopted, the minimum vaccination rate is 0.146.