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1.
Heliyon ; 10(5): e26972, 2024 Mar 15.
Artigo em Inglês | MEDLINE | ID: mdl-38444489

RESUMO

Due to the influence of structural clearances, the shearer's oscillates and jumps concerning the scraper are frequent, which induces the collision and vibration impact of the traction components and exacerbates the traction failure of the shearer. Therefore, to explore the correlation between attitude disturbance and traction vibration, an experiment on the traction vibration is carried out, the spatial swaying of the shearer and vibration differences between two traction components are obtained, the influence of the lifting angle of the rocker arm is discussed, and the influence mechanism of the shearer attitude disturbance on traction vibration is elucidated. The results indicate that the rolling swing intensity of the shearer is the highest while the yawing swing intensity is the lowest, and the pitch swing intensity increases with the increase of the lifting angle of the rocker arm. Besides, the vibration impact indices of the two walking mechanisms have a competitive relationship of one decreasing but the other increasing, which can be used as a reference signal to judge the rolling swing and load-sharing performance of the traction part. Moreover, with the swing attitude, the competitive relationship of the average of vibration peaks is shown in the two support shoes, and it can be used as a reference signal to judge the pitching swing and the load-sharing performance of the traction part. This result reveals the impact mechanism of attitude disturbances on traction vibration and proposes a signal monitoring approach for judging the traction attitude disturbance and load-sharing performance, providing a reference for reducing traction faults.

2.
ACS Omega ; 7(4): 3656-3670, 2022 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-35128274

RESUMO

The existing research on coal gangue identification based on vibration usually assumes that coal gangue particles are ideal shapes. To understand the vibration response difference in hydraulic support caused by coal and gangue with real shapes, this paper uses a three-dimensional (3D) scanning technology to determine the real shape of coal particles. The process of coal and gangue impacting the tail beam at different angles was simulated in the LS-DYNA software package, and the effects of shape parameters, velocity, and coal strength on the difference in vibration signals caused by the two were analyzed statistically. The conclusions are as follows: the vibrational response of the tail beam is concentrated mainly in the area between the ribs. The regularity of the velocity signal caused by gangue is better than the regularity of the velocity signal caused by coal, and the attenuation speed of the acceleration signal of gangue is slower than the attenuation speed of the acceleration signal of coal. The probability distributions of the velocity and acceleration responses were analyzed statistically, and the results show that the results from coal can be well fitted by a logarithmic normal function, and the standard deviations of velocity and acceleration are 0.05591 and 489.8, respectively. The gangue results are fitted by the gamma function and the Weibull function, and the standard deviations are 0.13531 and 737.9, respectively, showing that the fitting function has the potential to be used as the basis for coal gangue identification. The change in coal strength has little effect on the vibration response of the tail beam. With increasingly falling velocity, the vibration signal intensity of the tail beam increases, but the discrimination between coal and gangue weakens; therefore, measures should be taken to reduce the falling velocity of the rock mass. The research results of this paper can provide a reference for further study of coal gangue identification methods based on vibration.

3.
Medicine (Baltimore) ; 99(49): e23496, 2020 Dec 04.
Artigo em Inglês | MEDLINE | ID: mdl-33285756

RESUMO

RATIONALE: Rituximab is a monoclonal antibody directed against B cells and is a first-line agent for the treatment of B cell lymphoma and a second-line agent for the treatment of idiopathic thrombocytopenic purpura (ITP). It has also been used for the treatment of several other autoimmune diseases. Epidermolysis bullosa acquisita (EBA) has never been reported as an adverse effect resulted from rituximab therapy. PATIENT CONCERNS: A 54-year-old female presented with relapse of the ITP for around eight months. She was treated with rituximab. Intramuscular chlorpheniramine and intravenous methylprednisolone and cimetidine were used as premedication before rituximab infusion. The infusion was initially started at 50 mg/h for 1 h followed by 100 mg/h till the end of infusion. The day after rituximab infusion, the patient noticed pruritic blisters on both arms and chest skin. The next day, the lesions increased in severity and extent. DIAGNOSIS: The skin biopsy established the diagnosis of EBA. H&E staining revealed subepidermal blisters infiltrated by inflammatory cells, including eosinophils and lymphocytes. Direct immunofluorescence (DIF) showed linear deposition of IgG and C3 at the dermoepidermal junction. Indirect immunofluorescence with the patient's serum on salt-split skin revealed exclusive dermal binding of circulating IgG antibasement membrane antibodies at a titer of 1:160. INTERVENTIONS: She was treated with intravenous methylprednisolone and was continued on oral prednisolone. OUTCOMES: The lesions regressed. Six weeks later, she had a recurrence of similar lesions but in milder form. This episode subsided in 4 to 5 days with topical steroid application. LESSONS: Physicians should consider this diagnosis when a patient develops bullous skin eruptions while undergoing Rituximab therapy.


Assuntos
Epidermólise Bolhosa Adquirida/induzido quimicamente , Fatores Imunológicos/efeitos adversos , Púrpura Trombocitopênica Idiopática/tratamento farmacológico , Rituximab/efeitos adversos , Feminino , Humanos , Pessoa de Meia-Idade
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