Hepatorenal index for grading liver steatosis with concomitant fibrosis.

INTRODUCTION: Ultrasonography is widely used as the first tool to evaluate fatty liver disease, and the hepatorenal index is a semi-quantitative method that improves its performance. Fibrosis can co-exist with steatosis or even replace it during disease progression. This study aimed to evaluate the influence of fibrosis on the measurement of steatosis using the hepatorenal index. MATERIALS AND METHODS: This cross-sectional study included 89 patients with nonalcoholic fatty liver disease and in whom liver fibrosis was determined by ultrasound elastography. The Pearson's correlation coefficient was used to compare between the results of the sonographic hepatorenal index and the quantification of steatosis using magnetic resonance spectroscopy as well the accuracy of detecting moderate to severe steatosis using sonography in two groups of patients: (A) without advanced fibrosis and (B) with advanced fibrosis. Advanced fibrosis was defined as a shear wave speed ≥ 1.78 m/s on ultrasound elastography. We calculated the area under the curve (AUC-ROC) to detect the ability of the hepatorenal index to differentiate light from moderate to severe steatosis in both groups. Moderate to severe steatosis was defined as a fat fraction > 15% on the magnetic resonance spectroscopy. The intra-observer variability was assessed using the Bland-Altman plot. RESULTS: Among patients, the mean age was 54.6 years and 59.6% were women, 50.6% had a body mass index ≥ 30 kg/m2, 29.2% had moderate to severe steatosis, and 27.2% had advanced fibrosis. There was a correlation between steatosis grading by ultrasonography and magnetic resonance in group A (0.73; P < 0.001), but not in Group B (0.33; P = 0.058). The AUC-ROC for detecting a steatosis fraction ≥ 15% was 0.90 and 0.74 in group A and group B, respectively. The intra-observer variability for the hepatorenal index measurements was not significant (-0.036; P = 0.242). CONCLUSION: The hepatorenal index is not appropriate for estimating steatosis in livers with advanced fibrosis.

Trauma in Curitiba: multifactorial assessment of victims admitted to a university hospital. / Trauma em Curitiba: avaliação multifatorial de vítimas admitidas em um hospital universitário.

OBJECTIVE: to describe the epidemiological profile of trauma patients admitted to a referral hospital in Curitiba (PR). Also, to investigate trauma mechanisms and to evaluate trauma severity scores. METHODS: descriptive observational cross-sectional study. Data were collected by applying a questionnaire to victims admitted in the emergency room from December 2016 to February 2018. RESULTS: a total of 1354 trauma victims were included in the study, of which 60% were transported by SIATE and 40% by SAMU. Regarding gender, 70% of the patients were male. The mean age was 39.48 years. About the time and day of the calls, the largest proportion was concentrated on Friday night. In relation to the mechanism of trauma, in patients transported by SIATE, the most frequent in men was motorcycle collision (34.3%), while in women was same-level fall (21.42%). In SAMU, the most frequent mechanism regardless of gender was same-level fall (20.06% and 40.66%, respectively). Analyzing the severity scores, it was observed that 95.5% of the patients were classified as mild by the Glasgow Coma Scale. CONCLUSION: the profile of trauma victims analyzed in this large study is quite similar to what other national smaller studies have already described: young men victims of traffic accidents. Therefore, the economically active population is the most affected, reflecting in high cost to society.

OBJETIVO: descrever o perfil epidemiológico das vítimas de trauma atendidas em um hospital de referência no município de Curitiba (PR), bem como investigar os mecanismos do trauma, além de avaliar os escores de gravidade. MÉTODOS: estudo descritivo observacional transversal, cujos dados foram obtidos através da aplicação de questionário em vítimas atendidas na sala de emergência, entre dezembro de 2016 e fevereiro de 2018. RESULTADOS: foram incluídos no estudo 1354 vítimas de trauma, das quais 60% tiveram como transporte pré-hospitalar o Serviço Integrado de Atendimento ao Trauma em Emergência (SIATE), e 40%, o Serviço de Atendimento Móvel de Urgência (SAMU). Quanto ao sexo, 70% dos pacientes eram do sexo masculino. A média de idade foi de 39,48 anos. Sobre o horário e dia dos atendimentos, a maior proporção se concentrou no período noturno na sexta-feira. Quanto ao mecanismo do trauma, nos pacientes atendidos pelo SIATE, o mais frequente em homens foi a colisão de motocicleta (34,3%), enquanto que em mulheres foi a queda de mesmo nível (21,42%). Já no SAMU, o mecanismo mais frequente independentemente do sexo foi queda de mesmo nível (20,06% e 40,66%, respectivamente). Analisando-se os escores de gravidade, observou-se que 95,5% dos pacientes eram classificados como leves pela escala de coma de Glasgow. CONCLUSÕES: o perfil das vítimas analisadas neste grande estudo muito se assemelha a outros estudos nacionais menores: homens, jovens, vítimas de acidentes de trânsito. A população economicamente ativa, portanto, é a mais afetada, refletindo em alto custo para a sociedade.

O real cirurgião de resgate: relatos de casos de um hospital universitário em Curitiba-PR-Brasil / The real rescue surgery: case reports from a university hospital in Curitiba-PR-Brazil

INTRODUÇÃO: A cirurgia de resgate á baseada em alguns pilares básicos: trauma, cirurgia de emergência, cuidados intensivos cirúrgicos, cuidados nutricionais, cirurgia geral eletiva, resgate cirúrgico e retirar a sepse do abdome. Este modelo de tratamento cirúrgico demonstrou maior eficiência, menor tempo de operação e menor tempo de internação hospitalar. Este artigo aborda dois casos clínicos em que o modelo de cirurgia de resgate foi usado como base para o tratamento. OBJETIVO: A ênfase deste caso é demonstrar que há uma necessidade de uma equipe de cirurgiões prontos para atuar com base nos cinco pilares da cirurgia de resgate para manejar pacientes gravemente feridos. METODOLOGIA: Esse estudo se caracteriza por ser um relato de casos, com análise de prontuário de maneira retrospectiva. CONCLUSÃO: É importante reconhecer que, embora não haja consenso entre as diretrizes para o tratamento de algumas morbidades agudas, cada paciente deve ser tratado individualmente para reduzir a mortalidade intra-hospitalar

INTRODUCTION: Rescue surgery is based on some basic pillars: trauma, emergency surgery, surgical intensive care, elective general surgery and surgical rescue. This model of surgical treatment demonstrated greater efficiency, shorter operating time and shorter hospital stay. This article approach two clinical cases in which the rescue surgery model was used as the basis for treatment. OBJECTIVE: The emphasis of this case is to demonstrate that there is a need for a team of surgeons ready to act based on the five pillars of rescue surgery to manage severely injured patients. METHODOLOGY: This study is characterized by being a case report, with retrospective analysis of medical records. CONCLUSION: It is important to recognize that, although there is no consensus between the guidelines for the treatment of some acute morbidities, each patient must be treated individually to reduce in-hospital mortality

Trauma em Curitiba: avaliação multifatorial de vítimas admitidas em um hospital universitário / Trauma in Curitiba: multifactorial assessment of victims admitted to a university hospital

RESUMO Objetivo: descrever o perfil epidemiológico das vítimas de trauma atendidas em um hospital de referência no município de Curitiba (PR), bem como investigar os mecanismos do trauma, além de avaliar os escores de gravidade. Métodos: estudo descritivo observacional transversal, cujos dados foram obtidos através da aplicação de questionário em vítimas atendidas na sala de emergência, entre dezembro de 2016 e fevereiro de 2018. Resultados: foram incluídos no estudo 1354 vítimas de trauma, das quais 60% tiveram como transporte pré-hospitalar o Serviço Integrado de Atendimento ao Trauma em Emergência (SIATE), e 40%, o Serviço de Atendimento Móvel de Urgência (SAMU). Quanto ao sexo, 70% dos pacientes eram do sexo masculino. A média de idade foi de 39,48 anos. Sobre o horário e dia dos atendimentos, a maior proporção se concentrou no período noturno na sexta-feira. Quanto ao mecanismo do trauma, nos pacientes atendidos pelo SIATE, o mais frequente em homens foi a colisão de motocicleta (34,3%), enquanto que em mulheres foi a queda de mesmo nível (21,42%). Já no SAMU, o mecanismo mais frequente independentemente do sexo foi queda de mesmo nível (20,06% e 40,66%, respectivamente). Analisando-se os escores de gravidade, observou-se que 95,5% dos pacientes eram classificados como leves pela escala de coma de Glasgow. Conclusões: o perfil das vítimas analisadas neste grande estudo muito se assemelha a outros estudos nacionais menores: homens, jovens, vítimas de acidentes de trânsito. A população economicamente ativa, portanto, é a mais afetada, refletindo em alto custo para a sociedade.

ABSTRACT Objective: to describe the epidemiological profile of trauma patients admitted to a referral hospital in Curitiba (PR). Also, to investigate trauma mechanisms and to evaluate trauma severity scores. Methods: descriptive observational cross-sectional study. Data were collected by applying a questionnaire to victims admitted in the emergency room from December 2016 to February 2018. Results: a total of 1354 trauma victims were included in the study, of which 60% were transported by SIATE and 40% by SAMU. Regarding gender, 70% of the patients were male. The mean age was 39.48 years. About the time and day of the calls, the largest proportion was concentrated on Friday night. In relation to the mechanism of trauma, in patients transported by SIATE, the most frequent in men was motorcycle collision (34.3%), while in women was same-level fall (21.42%). In SAMU, the most frequent mechanism regardless of gender was same-level fall (20.06% and 40.66%, respectively). Analyzing the severity scores, it was observed that 95.5% of the patients were classified as mild by the Glasgow Coma Scale. Conclusion: the profile of trauma victims analyzed in this large study is quite similar to what other national smaller studies have already described: young men victims of traffic accidents. Therefore, the economically active population is the most affected, reflecting in high cost to society.

Successful endovascular management of a traumatic aortic rupture in a pediatric patient: case report and literature review.

We report herein an 11-year-old pedestrian struck by a motorcycle, who suffered subdural hematoma and aortic rupture and developed traumatic pseudoaneurysm. He was treated conservatively for the first 24 hours and submitted to stent placement occluding the aneurysm neck. There were no recurrences in the post-procedure period and the child was discharged after 21 days without sequelae. This report also reviews trauma mechanisms and management of such threatening lesions in the pediatric population.