Obesity among type 2 diabetes mellitus at Sidama Region, Southern Ethiopia.

BACKGROUND: Type 2 diabetes is becoming highly prevalent worldwide and it is one of the leading causes of mortality. The cause of mortality among these patients is mostly related to the dominant presence of modifiable cardiovascular risk factors such as obesity. The aim of the current study is therefore to determine the prevalence of obesity and its associated factors among patients with type 2 diabetes mellitus at Sidama region, Ethiopia. METHOD: Institution-based cross-sectional study design was implemented to determine the prevalence of obesity and its associated factor among patients with type two diabetes at Hawassa University Comprehensive Specialized Hospital and Yirgalem General Hospital from October 16 2018 to December 21, 2018. A simple random sampling technique was implemented to select 314 study participants. After obtaining consent, different patients' related data were collected using a questionnaire. Patients' records were also reviewed. 4ml of the blood sample was collected from each study participant and analyzed for lipid profile test. Blood glucose level was done using COBAS INTEGRA 6000. A binary logistic regression was used to assess factors that have an association with obesity. A P-value of <0.05 was considered statistically significant. RESULT: The majority of the study participants (67.2%) were male and 61.8% of the study participants were aged >45years. The overall prevalence of overweight and obesity among the study participants was 36.3% and 18.8% respectively. About 41% of the study participants have a normal BMI. Females were more obese (28.2% Vs 14.2%) than males and BMI stratification by sex was statistically significant (P = 0.02). Sex (AOR = 3.0, CI = 1.6-5.7, P-Value = 0.001) and TG (AOR = 3.6, CI = 1.6-8.3, P-Value = 0.003) are factors that were independently associated with obesity among type 2 DM patients. CONCLUSION: Overweight and obesity among type two diabetic patients were prevalent. In addition, obesity and overweight disorder are common among T2DM and gender and triglycerides levels were associated with obesity.

High prevalence and antimicrobial susceptibility pattern of salmonella species and extended-spectrum ß-lactamase producing Escherichia coli from raw cattle meat at butcher houses in Hawassa city, Sidama regional state, Ethiopia.

BACKGROUND: Food-borne diseases related to the consumption of meat and its products had public health importance worldwide. The problem became worst in Ethiopia as the result of the tradition of eating raw cattle meat. Salmonella species and Escherichia coli are important food-borne pathogens associated with meat contamination. Hence the current study aimed to assess the prevalence and antimicrobial susceptibility of Salmonella species and Extended-spectrum ß-lactamase producing Escherichia coli from raw cattle meat at butcher houses in Hawassa city, Sidama regional state, Ethiopia. METHOD: A cross-sectional study was done on the prevalence and antimicrobial susceptibility pattern of Salmonella species and Extended-spectrum ß-lactamase producing E.coli from raw cattle meat at butcher houses in Hawassa city from September to December 2020. Socio-demographic data were collected using a structured questionnaire and raw cattle meat and swab samples were collected from meat cutting equipment. The collected samples transported using icebox to Hawassa University College of Medicine and Health Sciences Microbiology Laboratory for identification. Samples were grown on different culture media and antimicrobial susceptibility tests were determined by using Kirby disc diffusion method. Data were entered and analyzed into SPSS version 23. Descriptive statistics were done and P-value < 0.05 was considered as statistically significant. RESULT: The overall prevalence of salmonella and ESBL producing E.coli among 556 samples collected from 278 butcher houses was 36 (6.47%) (95% CI: 1.68-1.79) of which 13 (2.3%) were ESBL producing E.coli and 23(4.1%) were salmonella species. Poor hand washing practice (AOR = 2.208; 95% CI: 1.249-3.904) and touching birr while selling meat (AOR = 0.75; 95% CI: (0.433-1.299) were found to be significantly associated with the prevalence of salmonella species and E.coli on cattle meat. The isolates showed moderate levels of resistance (60-70%) against Amoxicillin/ clavulanic acid and high susceptibility (85-100%) against gentamicin, cotrimoxazole, ceftazidime, and tetracycline and the overall multidrug resistance was 33.3%. CONCLUSION: This study revealed moderately high prevalence of salmonella and E.coli due to poor hygiene and sanitation practices in the butcher shops. Furthermore, the existence of ESBL producing E.coli isolates clearly indicate the possible threat to public health. Therefore, inspection by the right agencies must be implemented in order to prevent food-borne outbreaks and antimicrobial resistance.

Assessment of Knowledge, Attitude, and Practice towards Prevention and Control of Malaria in Halaba Town, Southern Ethiopia, 2017.

BACKGROUND: Malaria is one of the primary public health problems in Ethiopia. Therefore, assessment of situation of the disease and communities' knowledge and perceptions about this disease is necessary to introduce appropriate preventive and control measures. Hence, this study was aimed to assess the knowledge, attitude, and practice towards malaria in Halaba town, SNNPR, Ethiopia. METHODS: A community-based cross-sectional study was conducted in Halaba town from June 2017 to September 2017. A multistage random sampling technique was used to select the study participants. A total of 421 were interviewed to assess their knowledge, attitude, and practice towards malaria. RESULTS: About 280 (66.5%) respondents had ever heard of malaria. Most of the respondents (63.4%) attributed the cause of malaria to mosquito bites. However, some of the respondents (36.6%) mentioned contact with malaria patients, lack of personal hygiene, staying together, and transmission via breathing as the causes of malaria. Sleeping under mosquito nets, draining stagnant water, and indoor residual spraying were the most frequently mentioned malaria preventive measures perceived and practiced by the respondents. CONCLUSIONS: A high level of knowledge about the cause, transmission, and preventive methods of malaria was detected among the community in Halaba town. However, a significant proportion had misconceptions about the cause and transmission of malaria suggesting the necessity of health education to raise the community's awareness about the disease.

Magnitude, Severity, and Associated Factors of Anemia among Under-Five Children Attending Hawassa University Teaching and Referral Hospital, Hawassa, Southern Ethiopia, 2016.

BACKGROUND: Anemia is a widespread public health problem associated with increased risk of morbidity and mortality. Infants, under-5-year-old children, and pregnant women have greater susceptibility to anemia. The magnitude and associated risk factors for anemia vary in different settings. The study aimed to assess the magnitude, severity, and associated factors of anemia at Hawassa University Teaching and Referral hospital, Hawassa, southern Ethiopia. METHODS: In a hospital-based cross-sectional study, a total of 422 under-five children were included. Sociodemographic data and other predisposing factors were collected by structured questionnaire. Venous blood samples were collected and analyzed for hemoglobin determination using a Cell-Dyn 1800 automated analyzer. Stool samples were collected and processed using direct wet mount and formol-ether concentration method to detect intestinal parasites. Data were entered and analyzed using SPSS version 20 statistical packages. Binary and multiple logistic regressions were computed to assess factors associated with anemia. p value less than 0.05 was taken as statistically significant. RESULT: The overall prevalence of anemia was found to be 41.7%. The mean hemoglobin level was 10.59 g/dl. Anemia was of mild, moderate, and severe type in 6.6%, 19%, and 16.1% of the children, respectively. Children in the age group 6-23 months (AOR = 2.04 (95% CI: 1.13, 3.69)), and mothers having no formal education (AOR = 1.73 (95% CI: 0.99, 3.02)) were identified as associated factors for anemia. CONCLUSION: The prevalence of anemia among the study subjects was 41.7% indicative of the fact that anemia is an important public health problem. It was associated with the child's age, residence, mother's education level, and intestinal parasite (Ascaris lumbricoides). It clearly indicates that there should be well integrated public health interventions to improve the health status that needs to be prioritized to prevent anemia among children under five years of age.

Prevalence of intestinal parasitic infections in Hawassa University students' clinic, Southern Ethiopia: a 10-year retrospective study.

OBJECTIVE: The purpose of this study was to determine the prevalence of intestinal parasitic infections among patients who had attended Hawassa University students' clinic, Southern Ethiopia. RESULT: Over the 10 years period, a total of 13,679 patients visiting Hawassa University students' clinic were included in the study. A total of 6553 (47.9%) patients were positive for at least one intestinal parasite. The overall prevalence of intestinal helminth and protozoan infections was 20.3% and 27.6% respectively. There were four dual infections and one triple infection. E. histolytica/E. dispar trophozoite was the most common identified parasite, which was seen in 18% of the patients while Enterobius vermicularis (0.1%) was the least reported parasite. Other parasites identified were Ascaris lumbricoides (15.0%), Hookworm species (2.0%), Taenia species (1.8%), Hymenolepis nana (0.7%), Strongyloides stercoralis (0.3%), Trichuris trichuria (0.2%), and Shistosoma mansoni (0.2%). The prevalence of helminthes was higher in females (23.3%) than in males (19.5%) (P < 0.00001) while that of protozoan infections was 28.5% in males than females (23.8%) (574/2414) (P < 0.00001).

Schistosoma mansoni infection and risk factors among the fishermen of Lake Hawassa, southern Ethiopia.

Schistosomiasis is a neglected tropical parasitic disease caused by different species of genus Schistosoma. Schistosoma mansoni causes a severe intestinal parasitic infection of high public and medical importance in Ethiopia. This study aimed to determine the prevalence of, and risk factors for, S. mansoni infection among the fishermen of Lake Hawassa, southern Ethiopia, using a cross-sectional study design. A total of 243 fishermen were selected from the Hawassa Town Fishermen Association's list in 2013. Data on socio-demographic characteristics and risk factors were collected from the fishermen using semi-structured questionnaires. Stool samples were collected and processed using the Kato-Katz thick smear technique. The overall prevalence of S. mansoni among the fishermen was 29.21% and the mean intensity of infection was 158.88 eggs per gram (EPG). The overall prevalence of intestinal helminths, including S. mansoni, was 69.54%. Similar prevalences of S. mansoni were recorded in age groups 15-19, 20-24 and 25-29 years: 31.82%, 31.75% and 31.94%, respectively. Fishermen who swam a minimum of once a week in Lake Hawassa were 2.92 times (95% CI: 1.554, 5.502) more likely to have acquired S. mansoni infection than those who swam in the lake less than once a week. The results indicate moderate endemicity of S. mansoni infection among the fishermen of Lake Hawassa. These fishermen could be a potentially high-risk group for S. mansoni infection and might be responsible for the transmission of infection to other segments of the community visiting the lake for recreation. Moreover, a high prevalence of soil-transmitted helminths (STHs) was recorded among the fishermen. Integrated prevention and control strategies for schistosomiasis and STHs by different sectors are needed to tackle this problem.