[Primary systemic amyloidosis with exclusive involvement of the tongue as an exceptional cause of dysphagia]. / Amiloidosis primaria AL con afección exclusiva de la lengua como causa excepcional de disfagia.

We present a 73-year-old woman with progressive dysphagia and dysarthria over two years associated with systemic symptoms including weight loss, asthenia and dyspnoea. Biopsy of the tongue demonstrated amyloid AL deposits. The immunohistochemical study showed a notable positiveness to antibodies for L-kappa chains. The patient died 6 months after diagnosis.

Amiloidosis primaria AL con afección exclusiva de la lengua como causa excepcional de disfagia / Primary systemic amyloidosis with exclusive involvement of the tongue as an exceptional cause ofdysphagia

Se presenta el caso de una mujer de 73 años de edad con disfagia progresiva asociada a disartria de 2 años de evolución, con síntomas sistémicos que incluían disnea, astenia y pérdida de peso. Se realizó biopsia de la lengua que mostró amiloidosis primaria AL. En el estudio inmunohistoquímico se obtuvo una marcada positividad con anticuerpos frente a cadenas ligeras kappa. La paciente falleció a los 6 meses del diagnóstico (AU)

We present a 73-year-old woman with progressive dysphagia and dysarthria over two years associated with systemic symptoms including weight loss, asthenia and dyspnoea. Biopsy of the tongue demonstrated amyloid AL deposits. The immunohistochemical study showed a notable positiveness to antibodies for L-kappa chains. The patient died 6 months after diagnosis (AU)