Assuntos
Atrazina , Herbicidas , Prometrina , Poluentes do Solo , Combinação de Medicamentos , Microbiologia do SoloRESUMO
Triazine chloro derivatives: atrazine, simazine manifest no mutagenic and recombinogenic properties in yeasts; triazine methylthio derivatives: prometryne, semeron (desmetryne) generate both genetic events with low concentrations of 0.5 and 5 mg/l. It is found that prometryne is more able to generate point mutations, while semeron--to generate mitotic recombinations. In this case frequency of experimental prototrophs is twice higher than the control level.
Assuntos
Herbicidas/farmacologia , Saccharomyces cerevisiae/efeitos dos fármacos , Triazinas , Relação Dose-Resposta a Droga , Mitose/efeitos dos fármacos , Mutação , Recombinação Genética/efeitos dos fármacos , Saccharomyces cerevisiae/citologia , Saccharomyces cerevisiae/genéticaRESUMO
Changes in yeast cells induced by the fungicide zineb were studied using biochemical, genetic techniques and electron microscopy. The primary changes involved anabolic processes since RNA and protein content increased in the cells. The data were consistent with a larger size of mitochondria. The oxidative-reductive activity of cell extracts did not change under the action of the fungicide. Zineb at a concentration of 0.5 to 50 mg/litre exerted a genetic activity towards indicator microorganisms. The changes in the morphophysiological characteristics of yeast growth under the action of zineb are presumed to be of a protective nature. Zineb traces in soil must be controlled in terms of the microbiological index.