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1.
Phys Rev Lett ; 121(17): 173603, 2018 Oct 26.
Artigo em Inglês | MEDLINE | ID: mdl-30411925

RESUMO

We observe a sixfold Purcell broadening of the D_{2} line of an optically trapped ^{87}Rb atom strongly coupled to a fiber cavity. Under external illumination by a near-resonant laser, up to 90% of the atom's fluorescence is emitted into the resonant cavity mode. The sub-Poissonian statistics of the cavity output and the Purcell enhancement of the atomic decay rate are confirmed by the observation of a strongly narrowed antibunching dip in the photon autocorrelation function. The photon leakage through the higher-transmission mirror of the single-sided resonator is the dominant contribution to the field decay (κ≈2π×50 MHz), thus offering a high-bandwidth, fiber-coupled channel for photonic interfaces such as quantum memories and single-photon sources.

2.
Phys Rev Lett ; 119(18): 180503, 2017 Nov 03.
Artigo em Inglês | MEDLINE | ID: mdl-29219582

RESUMO

We demonstrate the parallel and nondestructive readout of the hyperfine state for optically trapped ^{87}Rb atoms. The scheme is based on state-selective fluorescence imaging and achieves detection fidelities >98% within 10 ms, while keeping 99% of the atoms trapped. For the readout of dense arrays of neutral atoms in optical lattices, where the fluorescence images of neighboring atoms overlap, we apply a novel image analysis technique using Bayesian inference to determine the internal state of multiple atoms. Our method is scalable to large neutral atom registers relevant for future quantum information processing tasks requiring fast and nondestructive readout and can also be used for the simultaneous readout of quantum information stored in internal qubit states and in the atoms' positions.

3.
Phys Rev Lett ; 119(16): 160401, 2017 Oct 20.
Artigo em Inglês | MEDLINE | ID: mdl-29099213

RESUMO

Quantum statistics have a profound impact on the properties of systems composed of identical particles. At the most elementary level, Bose and Fermi quantum statistics differ in the exchange phase, either 0 or π, which the wave function acquires when two identical particles are exchanged. In this Letter, we demonstrate that the exchange phase can be directly probed with a pair of massive particles by physically exchanging their positions. We present two protocols where the particles always remain spatially well separated, thus ensuring that the exchange contribution to their interaction energy is negligible and that the detected signal can only be attributed to the exchange symmetry of the wave function. We discuss possible implementations with a pair of trapped atoms or ions.

4.
Clin Genet ; 92(1): 45-51, 2017 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-28032339

RESUMO

Maternal uniparental disomy of chromosome 16 [upd(16)mat] as the result of trisomy 16 is one of the most frequently reported uniparental disomies in humans, but a consistent phenotype is not obvious. Particularly, it is difficult to discriminate between features resulting from upd(16)mat and mosaic trisomy 16. By evaluating literature data (n = 74) and three own cases we aimed to determine whether the clinical features are due to upd(16)mat or to trisomy 16 mosaicism. While in single cases the clinical symptoms were caused by homozygosity of autosomal recessive mutations on chromosome 16, it turned out that clinical features in upd(16)mat are caused by (hidden) trisomy 16 mosaicism and a specific chromosome 16-associated imprinting disorder does not exist. In trisomy 16/upd(16)mat pregnancies, the management should be based on the ultrasound results and on the clinical course of the pregnancy. In fact, mosaic trisomy 16 pregnancies require a close monitoring because of the higher risk for hypertensive disorders. Postnatal testing for upd(16)mat should be considered in case of homozygosity for an autosomal-recessive mutation, in individuals carrying chromosome 16 aberrations and in phenotypes comprising features of the trisomy 16/upd(16)mat spectrum. Finally, upd(16)mat probably represents a bioindicator for a hidden trisomy 16 mosaicism.


Assuntos
Cromossomos Humanos Par 16/genética , Trissomia/genética , Dissomia Uniparental/genética , Pré-Escolar , Impressão Genômica/genética , Humanos , Masculino , Herança Materna/genética , Mosaicismo , Trissomia/fisiopatologia , Dissomia Uniparental/fisiopatologia
5.
Opt Express ; 20(12): 12710-20, 2012 Jun 04.
Artigo em Inglês | MEDLINE | ID: mdl-22714300

RESUMO

The internal state of organic photochromic spiropyran molecules adsorbed on optical microfibres is optically controlled and measured by state-dependent light absorption. Repeated switching between the states is achieved by exposure to the evanescent field of a few nanowatts of light guided in the microfibre. By adjusting the microfibre evanescent field strength the dynamic equilibrium state of the molecules is controlled. Time-resolved photoswitching dynamics are measured and modelled with a rate equation model. We also study how many times the photochromic system can be switched before undergoing significant photochemical degradation.

6.
Opt Express ; 19(22): 21205-10, 2011 Oct 24.
Artigo em Inglês | MEDLINE | ID: mdl-22108972

RESUMO

We apply the Collins-Huygens integral to analytically describe propagation of a doughnut beam generated by a spiral phase plate. Measured beam profiles in free space and through an ABCD-lens system illustrate excellent agreement with theory. Applications range from the creation of optical beams with angular momentum to microscopy to trapping neutral atoms. The method extends to other beam shaping components, too.

7.
Phys Rev Lett ; 103(12): 123006, 2009 Sep 18.
Artigo em Inglês | MEDLINE | ID: mdl-19792433

RESUMO

We experimentally investigate the spin dynamics of one and two neutral atoms strongly coupled to a high finesse optical cavity. We observe quantum jumps between hyperfine ground states of a single atom. The interaction-induced normal-mode splitting of the atom-cavity system is measured via the atomic excitation. Moreover, we observe the mutual influence of two atoms simultaneously coupled to the cavity mode.

8.
Phys Rev Lett ; 102(5): 053001, 2009 Feb 06.
Artigo em Inglês | MEDLINE | ID: mdl-19257509

RESUMO

We overcome the diffraction limit in fluorescence imaging of neutral atoms in a sparsely filled one-dimensional optical lattice. At a periodicity of 433 nm, we reliably infer the separation of two atoms down to nearest neighbors. We observe light induced losses of atoms occupying the same lattice site, while for atoms in adjacent lattice sites, no losses due to light induced interactions occur. Our method points towards characterization of correlated quantum states in optical lattice systems with filling factors of up to one atom per lattice site.

9.
Phys Rev Lett ; 99(16): 163602, 2007 Oct 19.
Artigo em Inglês | MEDLINE | ID: mdl-17995250

RESUMO

The strong evanescent field around ultrathin unclad optical fibers bears a high potential for detecting, trapping, and manipulating cold atoms. Introducing such a fiber into a cold-atom cloud, we investigate the interaction of a small number of cold cesium atoms with the guided fiber mode and with the fiber surface. Using high resolution spectroscopy, we observe and analyze light-induced dipole forces, van der Waals interaction, and a significant enhancement of the spontaneous emission rate of the atoms. The latter can be assigned to the modification of the vacuum modes by the fiber.

10.
Opt Express ; 15(19): 11952-8, 2007 Sep 17.
Artigo em Inglês | MEDLINE | ID: mdl-19547558

RESUMO

The guided modes of sub-wavelength diameter air-clad optical fibers exhibit a pronounced evanescent field. The absorption of particles on the fiber surface is therefore readily detected via the fiber transmission. We show that the resulting absorption for a given surface coverage can be orders of magnitude higher than for conventional surface spectroscopy. As a demonstration, we present measurements on sub-monolayers of 3,4,9,10-perylene-tetracarboxylic dianhydride (PTCDA) molecules at ambient conditions, revealing the agglomeration dynamics on a second to minutes timescale.

11.
Phys Rev Lett ; 97(24): 243003, 2006 Dec 15.
Artigo em Inglês | MEDLINE | ID: mdl-17280277

RESUMO

We recently demonstrated that strings of trapped atoms inside a standing wave optical dipole trap can be rearranged using optical tweezers [Y. Miroshnychenko, Nature 442, 151 (2006)]. This technique allows us to actively set the interatomic separations on the scale of the individual trapping potential wells. Here, we use such a distance-control operation to insert two atoms into the same potential well. The detected success rate of this manipulation is 16(-3)(+4)%, in agreement with the predictions of a theoretical model based on our experimental parameters.

12.
Phys Rev Lett ; 95(3): 033002, 2005 Jul 15.
Artigo em Inglês | MEDLINE | ID: mdl-16090739

RESUMO

We optically detect the positions of single neutral cesium atoms stored in a standing wave dipole trap with a subwavelength resolution of 143 nm rms. The distance between two simultaneously trapped atoms is measured with an even higher precision of 36 nm rms. We resolve the discreteness of the interatomic distances due to the 532 nm spatial period of the standing wave potential and infer the exact number of trapping potential wells separating the atoms. Finally, combining an initial position detection with a controlled transport, we place single atoms at a predetermined position along the trap axis to within 300 nm rms.

14.
Phys Rev Lett ; 93(15): 150501, 2004 Oct 08.
Artigo em Inglês | MEDLINE | ID: mdl-15524857

RESUMO

We demonstrate the realization of a quantum register using a string of single neutral atoms which are trapped in an optical dipole trap. The atoms are selectively and coherently manipulated in a magnetic field gradient using microwave radiation. Our addressing scheme operates with a high spatial resolution, and qubit rotations on individual atoms are performed with 99% contrast. In a final readout operation we analyze each individual atomic state. Finally, we have measured the coherence time and identified the predominant dephasing mechanism for our register.

15.
Phys Rev Lett ; 91(21): 213002, 2003 Nov 21.
Artigo em Inglês | MEDLINE | ID: mdl-14683295

RESUMO

We have prepared and detected quantum coherences of trapped cesium atoms with long dephasing times. Controlled transport by an "optical conveyor belt" over macroscopic distances preserves the atomic coherence with slight reduction of coherence time. The limiting dephasing effects are experimentally identified, and we present an analytical model of the reversible and irreversible dephasing mechanisms. Our experimental methods are applicable at the single-atom level. Coherent quantum bit operations along with quantum state transport open the route towards a "quantum shift register" of individual neutral atoms.

17.
Opt Express ; 11(25): 3498-502, 2003 Dec 15.
Artigo em Inglês | MEDLINE | ID: mdl-19471484

RESUMO

We have continuously imaged the controlled motion of a single atom as well as of a small number of distinguishable atoms with observation times exceeding one minute. The Cesium atoms are confined to potential wells of a standing wave optical dipole trap which allows to transport them over macroscopic distances. The atoms are imaged by an intensified CCD camera, and spatial resolution near the diffraction limit is obtained.

18.
Phys Rev Lett ; 88(8): 083601, 2002 Feb 25.
Artigo em Inglês | MEDLINE | ID: mdl-11863954

RESUMO

In atom lithography with optical masks, deposition of an atomic beam on a given substrate is controlled by a standing light-wave field. The lateral intensity distribution of the light field is transferred to the substrate with nanometer scale. We have tailored a complex pattern of this intensity distribution through diffraction of a laser beam from a hologram that is stored in a photorefractive crystal. This method can be extended to superpose 1000 or more laser beams. The method is furthermore applicable during growth processes and thus allows full 3D structuring of suitable materials with periodic and non-periodic patterns at nanometer scales.

19.
Hum Reprod ; 16(8): 1648-52, 2001 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-11473957

RESUMO

BACKGROUND: There is an increased rate of chromosomal anomalies, in particular low-level sex chromosome mosaicism, in the female partners of couples undergoing intracytoplasmic sperm injection (ICSI). METHODS: Among 811 consecutive couples presenting for pre-ICSI chromosome analysis, chromosomal abnormalities were detected in 54 individuals, of which 26 were low-level sex chromosome mosaicism in the females. Attention was focused on the treatment course and outcome of ICSI in 20 couples with low-level sex chromosome mosaicism in the females actually embarking on ICSI treatment (group I, n = 38 ICSI treatment cycles). Applying a case-control design, each of the 20 couples was matched according to female age and source of spermatozoa to couples without a chromosomal abnormality in either of the partners (group II, n = 38 ICSI treatment cycles). RESULTS: No significant differences were found between the groups in ovarian response, fertilization rate and number of embryos transferred. Pregnancy rates, as well as implantation and abortion rates did not differ significantly between the groups. CONCLUSIONS: The data suggest that low-level sex chromosome mosaicism in females has no major effect on the course and outcome of ICSI.


Assuntos
Mosaicismo , Aberrações dos Cromossomos Sexuais , Injeções de Esperma Intracitoplásmicas , Resultado do Tratamento , Aborto Espontâneo , Implantação do Embrião , Transferência Embrionária , Estradiol/sangue , Feminino , Humanos , Infertilidade/genética , Cariotipagem , Masculino , Indução da Ovulação , Gravidez , Resultado da Gravidez
20.
Science ; 293(5528): 278-80, 2001 Jul 13.
Artigo em Inglês | MEDLINE | ID: mdl-11408622

RESUMO

We report the realization of a deterministic source of single atoms. A standing-wave dipole trap is loaded with one or any desired number of cold cesium atoms from a magneto-optical trap. By controlling the motion of the standing wave, we adiabatically transport the atom with submicrometer precision over macroscopic distances on the order of a centimeter. The displaced atom is observed directly in the dipole trap by fluorescence detection. The trapping field can also be accelerated to eject a single atom into free flight with well-defined velocities.

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