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1.
Phys Rev Lett ; 109(8): 085001, 2012 Aug 24.
Artigo em Inglês | MEDLINE | ID: mdl-23002750

RESUMO

An experimental study of hydrodynamic perturbation evolution in a strong unsupported shock wave, which is immediately followed by an expansion wave, is reported. A planar solid plastic target rippled on the front side is irradiated with a 350-450 ps long laser pulse. The perturbation evolution in the target is observed using face-on monochromatic x-ray radiography during and for up to 4 ns after the laser pulse. The theoretically predicted large oscillations of the areal mass in the target are observed for the first time. Multiple phase reversals of the areal mass modulation are detected.

2.
Am J Transplant ; 12(8): 1988-96, 2012 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-22682114

RESUMO

Public reports of organ transplant program outcomes by the US Scientific Registry of Transplant Recipients have been both groundbreaking and controversial. The reports are used by regulatory agencies, private insurance providers, transplant centers and patients. Failure to adequately adjust outcomes for risk may cause programs to avoid performing transplants involving suitable but high-risk candidates and donors. At a consensus conference of stakeholders held February 13-15, 2012, the participants recommended that program-specific reports be better designed to address the needs of all users. Additional comorbidity variables should be collected, but innovation should also be protected by excluding patients who are in approved protocols from statistical models that identify underperforming centers. The potential benefits of hierarchical and mixed-effects statistical methods should be studied. Transplant centers should be provided with tools to facilitate quality assessment and performance improvement. Additional statistical methods to assess outcomes at small-volume transplant programs should be developed. More data on waiting list risk and outcomes should be provided. Monitoring and reporting of short-term living donor outcomes should be enhanced. Overall, there was broad consensus that substantial improvement in reporting outcomes of transplant programs in the United States could and should be made in a cost-effective manner.


Assuntos
Transplante de Órgãos , Garantia da Qualidade dos Cuidados de Saúde , Humanos , Doadores Vivos
3.
Philos Trans A Math Phys Eng Sci ; 368(1916): 1739-68, 2010 Apr 13.
Artigo em Inglês | MEDLINE | ID: mdl-20211882

RESUMO

In inertial confinement fusion (ICF), the possibility of ignition or high energy gain is largely determined by our ability to control the Rayleigh-Taylor (RT) instability growth in the target. The exponentially amplified RT perturbation eigenmodes are formed from all sources of the target and radiation non-uniformity in a process called seeding. This process involves a variety of physical mechanisms that are somewhat similar to the classical Richtmyer-Meshkov (RM) instability (in particular, most of them are active in the absence of acceleration), but differ from it in many ways. In the last decade, radiographic diagnostic techniques have been developed that made direct observations of the RM-type effects in the ICF-relevant conditions possible. New experiments stimulated the advancement of the theory of the RM-type processes. The progress in the experimental and theoretical studies of such phenomena as ablative RM instability, re-shock of the RM-unstable interface, feedout and perturbation development associated with impulsive loading is reviewed.

4.
Phys Rev Lett ; 103(8): 085002, 2009 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-19792732

RESUMO

Experimental study of a shock-decelerated ablation front is reported. A planar solid plastic target is accelerated by a laser across a vacuum gap and collides with a lower-density plastic foam layer. While the target is accelerated, a fast Rayleigh-Taylor (RT) growth of the seeded single-mode perturbation at the ablation front is observed. After the collision, the velocity of the ablation front is seen to remain constant. The reshock quenches the RT growth but does not trigger any Richtmyer-Meshkov growth at the ablation front, which is shown to be consistent with both theory and simulations.

5.
Phys Rev E Stat Nonlin Soft Matter Phys ; 72(4 Pt 2): 046306, 2005 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-16383532

RESUMO

An expansion wave is produced when an incident shock wave interacts with a surface separating a fluid from a vacuum. Such an interaction starts the feedout process that transfers perturbations from the rippled inner (rear) to the outer (front) surface of a target in inertial confinement fusion. Being essentially a standing sonic wave superimposed on a centered expansion wave, a rippled expansion wave in an ideal gas, like a rippled shock wave, typically produces decaying oscillations of all fluid variables. Its behavior, however, is different at large and small values of the adiabatic exponent gamma. At gamma > 3, the mass modulation amplitude delta(m) in a rippled expansion wave exhibits a power-law growth with time alpha(t)beta, where beta = (gamma - 3)/(gamma - 1). This is the only example of a hydrodynamic instability whose law of growth, dependent on the equation of state, is expressed in a closed analytical form. The growth is shown to be driven by a physical mechanism similar to that of a classical Richtmyer-Meshkov instability. In the opposite extreme gamma - 1 << 1, delta(m) exhibits oscillatory growth, approximately linear with time, until it reaches its peak value approximately (gamma - 1)(-1/2), and then starts to decrease. The mechanism driving the growth is the same as that of Vishniac's instability of a blast wave in a gas with low . Exact analytical expressions for the growth rates are derived for both cases and favorably compared to hydrodynamic simulation results.

6.
Phys Rev Lett ; 87(26): 265001, 2001 Dec 24.
Artigo em Inglês | MEDLINE | ID: mdl-11800835

RESUMO

We report the first direct experimental observation of the ablative Richtmyer-Meshkov instability. It manifests itself in oscillations of areal mass that occur during the shock transit time, which are caused by the "rocket effect" or dynamic overpressure characteristic of interaction between the laser absorption zone and the ablation front. With the 4-ns-long Nike KrF laser pulse and our novel diagnostic technique (monochromatic x-ray imaging coupled to a streak camera) we were able to register a peak and a valley of the areal-mass variation before the observed onset of the Rayleigh-Taylor growth.

7.
Phys Rev Lett ; 87(26): 265002, 2001 Dec 24.
Artigo em Inglês | MEDLINE | ID: mdl-11800836

RESUMO

"Feedout" means the transfer of mass perturbations from the rear to the front surface of a driven target. When a planar shock wave breaks out at a rippled rear surface of the target, a lateral pressure gradient drives sonic waves in a rippled rarefaction wave propagating back to the front surface. This process redistributes mass in the volume of the target, forming the feedout-generated seed for ablative Rayleigh-Taylor (RT) instability. We report the first direct experimental observation of areal-mass oscillation associated with feedout, followed by the onset of exponential RT growth.

8.
Phys Rev Lett ; 66(11): 1442-1445, 1991 Mar 18.
Artigo em Inglês | MEDLINE | ID: mdl-10043210
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