RESUMO
The bronchoalveolar lavage (BAL) of two groups of hard metal workers (11 subjects) were examined and compared with BALs of 14 unexposed individuals as controls. The first group of workers included five asymptomatic subjects (2 females and 3 males) with normal lung function tests and chest X-rays. All the workers had been exposed daily to hard metal dust for 5 years before fiberoptic bronchoscopy. The second group of workers included six individuals (1 female and 5 males) with cobalt lung disease at biopsy. The BAL's cytology at the deep lung level is in agreement with a possible immunologic pathogenesis of the lung disease, similar to hypersensitivity pneumonitis (lymphocytosis with helper-suppressor ratio reduction). In order to identify diagnostic key-parameters, the data presented here are compared with data reported in literature for workers with a history of hard metal or cobalt (alone) exposure. Although the BAL can be useful, for a better definition of the reaction at the deep lung level, it seems insufficient per se for the diagnosis of hard metal lung disease.
Assuntos
Cobalto/efeitos adversos , Pneumopatias/patologia , Metalurgia , Doenças Profissionais/patologia , Exposição Ocupacional/efeitos adversos , Adulto , Líquido da Lavagem Broncoalveolar/citologia , Feminino , Humanos , Pneumopatias/induzido quimicamente , Masculino , Pessoa de Meia-Idade , Doenças Profissionais/induzido quimicamenteRESUMO
A total of 237 patients with AIDS have been observed in the infectious Disease Division of the United Hospitals of Bergamo during the past six years. Five patients (4.21%), suffering from TB and PCP, revealed PNX which was characterised by being bilateral and recurrent; it was a concomitant cause of death in 2 patients. The complications which occurred included acute pulmonary heart, pulmonary edema due to reexpansion and irreversible shock.
Assuntos
Síndrome da Imunodeficiência Adquirida/complicações , Pneumotórax/etiologia , Síndrome da Imunodeficiência Adquirida/mortalidade , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Pneumonia por Pneumocystis/complicações , Pneumotórax/mortalidade , Pneumotórax/terapia , Enfisema Pulmonar/complicações , Fibrose Pulmonar/complicações , Recidiva , Estudos Retrospectivos , Tuberculose Pulmonar/complicaçõesRESUMO
The authors examined 84 patients with pulmonary TBC treated with ethambutol (25 mg/Kg/die). The patients were divided into two groups on the basis of zinc plasma levels: 53 patients with zinc plasma level greater than 1 mg/l and 31 with zinc plasma levels less than 0.7 mg/l. The two groups underwent periodical follow-up of visual acuity, fundus, color vision (Fransworth 100 HUE) and visual field. The checks were monthly on the first group and fortnightly in the second. Eight patients presented signs of optic neuropathy. Patients with lower zinc plasma levels showed a higher percentage of optic neuropathy.
