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1.
Eur J Clin Microbiol Infect Dis ; 39(12): 2441-2445, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-32661809

RESUMO

Viral infections are common complications of pregnancy, with a wide range of obstetric and neonatal sequelae. Currently, there are limited data on whether SARS-CoV-2 is vertically transmitted in pregnant women tested positive for the virus. Here we describe a case of a known SARS-CoV-2-positive woman giving preterm birth to two fetuses with SARS-CoV-2 positive testing in placental tissue and amniotic fluid. The placental histological examinations showed chronic intervillositis and extensive intervillous fibrin depositions with ischemic necrosis of the surrounding villi.


Assuntos
Betacoronavirus/patogenicidade , Infecções por Coronavirus/transmissão , Diabetes Gestacional/diagnóstico , Transmissão Vertical de Doenças Infecciosas , Pneumonia Viral/transmissão , Complicações Infecciosas na Gravidez/diagnóstico , Nascimento Prematuro/virologia , Adulto , Líquido Amniótico/virologia , COVID-19 , Cesárea , Infecções por Coronavirus/diagnóstico , Infecções por Coronavirus/patologia , Infecções por Coronavirus/virologia , Diabetes Gestacional/patologia , Diabetes Gestacional/virologia , Feminino , Morte Fetal , Feto , Humanos , Pandemias , Placenta/patologia , Placenta/virologia , Pneumonia Viral/diagnóstico , Pneumonia Viral/patologia , Pneumonia Viral/virologia , Gravidez , Complicações Infecciosas na Gravidez/patologia , Complicações Infecciosas na Gravidez/virologia , Nascimento Prematuro/patologia , SARS-CoV-2 , Gêmeos Dizigóticos
5.
Twin Res ; 6(1): 7-11, 2003 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-12626222

RESUMO

To compare perinatal outcome of singleton versus twin pregnancies a matched cohort study was performed in Flanders, Belgium. All twins delivered in the region of Flanders during 1998-1999 were compared to singletons, matched for gestational age, fetal sex and maternal parity, resulting in 4384 infants in each group. Above 32 weeks of gestation, birthweight was significantly lower in twins (2095 +/- 364 g versus 2315 +/- 523 g; p < 0.001, 95% confidence interval 193 to 246 g). Perinatal mortality was also significantly lower in twins (1.98% versus 1.26%; odds ratio for twins 0.63; 95% confidence interval 0.53-0.75; p < 0.001 ), this was mostly due to fetal and not to early neonatal mortality. Congenital malformations occurred less frequently in twins (2.5% versus 3.7%; odds ratio for twins 0.80, 95% confidence interval 0.69-0.92; p = 0.001). From gestational age of 32 weeks on, respiratory distress syndrome was less frequent in twins (6.7% versus 8.0%; odds ratio for twins 0.81; 95% confidence interval 0.68-0.97; p = 0.011 ). No significant differences were noted with regard to intraventricular haemorrhage, neonatal infections and retinopathy of prematurity. Although twins have a lower birthweight, their outcome is more favorable compared to singletons, when matched for gestational age.


Assuntos
Resultado da Gravidez , Gravidez Múltipla/fisiologia , Gêmeos , Bélgica/epidemiologia , Peso ao Nascer , Estudos de Coortes , Anormalidades Congênitas/epidemiologia , Feminino , Humanos , Mortalidade Infantil , Recém-Nascido , Gravidez , Síndrome do Desconforto Respiratório do Recém-Nascido/epidemiologia
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