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2.
Vet Radiol Ultrasound ; 60(6): 734-744, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-31418983

RESUMO

The aim of this retrospective, cross-sectional, study was to evaluate clinical findings and outcomes for different ultrasonographic patterns of hepatic emphysema in dogs and cats. Dogs and cats with an ultrasonographic diagnosis of hepatic emphysema and a known outcome, from January 2010 to January 2018, were enrolled. The following data were recorded from medical and ultrasonographic records: ultrasonographic patterns of hepatic emphysema (parenchymal, portal venous, biliary), clinical signs, laboratory findings, and outcomes (favorable, poor). A total of 33 dogs and four cats met the inclusion criteria. Among these, 23 cases were classified as hepatic portal venous gas, 10 as parenchymal emphysema, and four as biliary emphysema. Clinical diagnosis categories were as follows: infection/sepsis (9), gastro-intestinal disease (9), iatrogenic (9), trauma (5), and liver neoplasia (5). An increase in serum liver enzymes was significantly associated with parenchymal emphysema (P = .03). Other clinical and laboratory findings were not associated with the type of hepatic emphysema. Hepatic portal venous gas was mostly transient in patients with ultrasonographic follow-up. The overall mortality was 40.5%. A significant difference was found between mortality by portal venous gas (21.7%) and mortality by parenchymal emphysema (90%) (P = .003). In conclusion, the ultrasonographic differentiation of hepatic emphysema between hepatic portal venous gas and parenchymal emphysema may be important for the prognosis of hepatic emphysema. The presence of parenchymal emphysema may be a poor prognostic indicator, while hepatic portal venous gas may be more benign. However, ultrasound findings should be carefully evaluated in the context of clinical findings.


Assuntos
Doenças do Gato/diagnóstico por imagem , Doenças do Cão/diagnóstico por imagem , Enfisema/veterinária , Gases , Hepatopatias/veterinária , Tecido Parenquimatoso/diagnóstico por imagem , Veia Porta/diagnóstico por imagem , Animais , Gatos , Estudos Transversais , Cães , Enfisema/diagnóstico por imagem , Feminino , Hepatopatias/diagnóstico por imagem , Masculino , Prognóstico , Estudos Retrospectivos , Ultrassonografia/veterinária
3.
Can J Vet Res ; 82(2): 154-158, 2018 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-29755196

RESUMO

The aim of this study was to evaluate the prevalence of hip and elbow dysplasia in a group of growing Labrador retrievers fed a fish-based diet enriched with nutraceuticals with chondroprotective properties. The puppies ranged from 3 to 12 mo of age and were divided into 2 groups, each fed a different diet. The control diet consisted of a high quality, chicken-based dog food, while the test diet was a fish-based dog food, enriched with nutraceuticals. Hip and elbow joints were radiographed and scored at 6 and 12 mo of age. Overall, 42 dogs completed the study. At 12 mo of age, no differences were found between the groups in the prevalence of hip and elbow dysplasia, although dogs fed the fish-based food enriched with nutraceuticals had a less severe grade of osteoarthritis at 12 mo. It was concluded that the fish-based diet with nutraceuticals did have beneficial effects on the development of severe osteoarthritis.


L'objectif de la présente étude était d'évaluer la prévalence de dysplasie de la hanche et du coude dans un groupe de chiens Labrador en croissance nourris avec une diète à base de poisson enrichie de neutraceutiques ayant des propriétés chondroprotectrices. L'âge des chiots variait de 3 à 12 mois et ils ont été divisés en deux groupes, chacun étant nourri avec une diète différente. La diète témoin consistait d'un aliment de haute qualité pour chien à base de poulet, alors que la diète test était un aliment pour chien à base de poisson et enrichi avec des neutraceutiques. Les articulations des hanches et des coudes ont été radiographiées à 6 et 12 mois d'âge. Un total de 42 chiens a complété l'étude. À 12 mois d'âge, aucune différence n'a été trouvée entre les groupes dans la prévalence de dysplasie de la hanche et du coude, bien que les chiens nourris avec la diète à base poisson enrichie de neutraceutiques avaient un score d'ostéoarthrite moins sévère à 12 mois. Il a été conclu que la diète à base de poisson enrichie de neutraceutiques avait des effets bénéfiques sur le développement d'ostéoarthrite sévère.(Traduit par Docteur Serge Messier).


Assuntos
Ração Animal/análise , Suplementos Nutricionais , Artropatias/veterinária , Osteoartrite/veterinária , Animais , Cães , Membro Anterior , Displasia Pélvica Canina/dietoterapia , Displasia Pélvica Canina/prevenção & controle , Artropatias/dietoterapia , Artropatias/prevenção & controle , Osteoartrite/dietoterapia , Osteoartrite/prevenção & controle
4.
Vet Radiol Ultrasound ; 58(6): E64-E67, 2017 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-27699974

RESUMO

A 13-year-old spayed female German shepherd dog was presented for acute onset of lethargy, anorexia, and disseminated erythematous skin lesions. Thoracic radiographs and abdominal ultrasonographic findings were consistent with metastatic hemangiosarcoma. Multiple, ill-defined, irregularly shaped hypoechoic nodules were also detected within the thoracic and abdominal wall. Hemangiosarcoma metastases to the skeletal muscle were confirmed based on histopathological examination. Multivisceral involvement was also confirmed by necropsy. Metastatic neoplasia should be considered as a differential diagnosis for dogs with ill-defined, irregular, hypoechoic, intramuscular nodules.


Assuntos
Doenças do Cão/patologia , Hemangiossarcoma/veterinária , Neoplasias Musculares/veterinária , Músculo Esquelético/patologia , Ultrassonografia/veterinária , Animais , Diagnóstico Diferencial , Doenças do Cão/diagnóstico por imagem , Cães , Feminino , Hemangiossarcoma/diagnóstico por imagem , Hemangiossarcoma/patologia , Neoplasias Musculares/diagnóstico por imagem , Neoplasias Musculares/secundário , Radiografia Torácica/veterinária
5.
Can Vet J ; 57(4): 382-6, 2016 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-27041755

RESUMO

A 12-year-old female dog with a 3-month history of poor response to diabetes treatment had an acute worsening of symptoms, including weakness and blindness. The dog had elevated blood glucose, alkaline phosphatase and urea concentration, hyposthenuria, glycosuria, hematuria, and pyuria. Escherichia coli was isolated from the urine. Radiographs and ultrasound examination showed that the dog had unilateral emphysematous pyelitis and concurrent cystitis associated with vesicoureteral reflux.


Pyélite emphysémateuse et cystite associées au reflux vésico-urétéral chez une chienne diabétique. Une chienne âgée de 12 ans avec une anamnèse de 3 mois de mauvaise réponse au traitement du diabète a présenté un aggravement aigu des symptômes, y compris de la faiblesse et de la cécité. La chienne avait une glycémie élevée, ainsi que des concentrations sériques élevées de la phosphatase alcaline et d'urée, de l'hyposthénurie, de la glycosurie, de l'hématurie et de la pyurie. Escherichia coli a été isolé de l'urine. Des radiographies et des échographies ont montré que la chienne était atteinte de pyélite emphysémateuse unilatérale et de cystite concomitante associées au reflux vésico-urétéral.(Traduit par Isabelle Vallières).


Assuntos
Complicações do Diabetes/veterinária , Enfisema/veterinária , Pielocistite/veterinária , Refluxo Vesicoureteral/veterinária , Animais , Complicações do Diabetes/urina , Cães , Enfisema/complicações , Escherichia coli/isolamento & purificação , Feminino , Pielocistite/etiologia , Pielocistite/urina , Refluxo Vesicoureteral/complicações , Refluxo Vesicoureteral/urina
6.
J Pharmacol Toxicol Methods ; 70(2): 163-9, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-25117630

RESUMO

INTRODUCTION: Gastrointestinal (GI) motility disorders include many clinical manifestations associated with various pathologies. They are widespread and can be considered a primary symptom or can be associated to other diseases, such as Parkinson's disease. Understanding the type and site of GI dysmotility is crucial to identify the functional abnormality and to unravel the underlying mechanisms, in order to design adequate therapeutic interventions. METHODS: In the present study, we applied radiological analysis, a common tool in clinical practice, to follow up in vivo the progression of GI dysmotility over time and along the entire GI tract in an animal model of central nervous dopaminergic degeneration and compared these results to those obtained with standard techniques commonly used to assess GI motor functions in small rodents. RESULTS: Our radiological data, showing delayed gastric emptying and constipation, agree with and expand previous information obtained with other functional assays in the same model, suggesting that radiological analysis can be an appropriate method to explore GI dysmotility in animal models of human pathologies. DISCUSSION: In this study we have applied for the first time the GI radiological analysis to an animal model of central nervous dopaminergic degeneration providing a non-invasive/animal-preserving approach, ethically more acceptable and useful to follow up the development of GI dysmotility in pathologies evolving over time.


Assuntos
Neurônios Dopaminérgicos/metabolismo , Neurônios Dopaminérgicos/patologia , Gastroenteropatias/diagnóstico por imagem , Animais , Modelos Animais de Doenças , Gastroenteropatias/induzido quimicamente , Gastroenteropatias/metabolismo , Masculino , Oxidopamina , Radiografia , Ratos , Ratos Sprague-Dawley
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