[Meningitis and chosen complications of neonatal period in preterm neonates born to single or multiple pregnancies]. / Neuroinfekcje a wybrane powiklania okresu noworodkowego u dzieci urodzonych przedwczesnie z ciaz pojedynczych i wieloplodowych.

UNLABELLED: The aim of this study was to determine the relationship between meningitis and neonatal period of complications such as massive intraventricular hemorrhage and into brain tissue, hypoxic-ischemic white matter injury retinopathy of prematurity 3-5 degrees and deafness in infants born prematurely from single and multiple pregnancies. MATERIAL: The retrospective study covered 460 preterm infants born to single pregnancies and 280 infants born prematurely with multiple pregnancies, hospitalized in the Clinic of Neonatology PUM in the years: 2005-2008. RESULTS: There were no statistically significant differences between the frequency of occurrence: peri/intraventricular hemorrhages (IVH) III degrees and IV degrees, hypoxic-ischemic injury in white matter, retinopathy of prematurity 3-5 degrees and hearing loss in newborns of both groups. Meningitis was diagnosed in 35 (7.92%) newborns from singleton pregnancy and in 9 (3.25%) with a multiple pregnancy. It was found that the risk of meningitis was significantly greater in infants with body weight less than 1000 grams (OR 4.18), and born under 28 weeks of gestation (OR = 5.07), regardless of group affiliation. We found a statistically significant correlation between the occurrence of meningitis and neonatal complications such as IVH III degrees and IV degrees (OR-5, 56), hypoxic-ischemic white matter injury (OR - 18.93) and retinopathy of prematurity (7.45) in newborns with both single and multiple pregnancies. There was no effect of meningitis on the incidence of hearing loss. CONCLUSION: There exists a significant association between the occurrence of meningitis and some neonatal complications such as massive intraventricular hemorrhage, hypoxic-ischemic changes in white matter of the brain and retinopathy of prematurity 3-5 degrees, leading to disturbances in the further development of the prematurely born child. The incidence of meningitis in newborn infants is inversely proportional to the duration of pregnancy.

Polypectomy followed by adjuvant chemotherapy in a patient with sarcoma botryoides of the uterine cervix--case report and review of the literature.

BACKGROUND: Embryonal rhabdomyosarcoma in a form of a polyp of the uterine cervix occurs mainly in young women in their second decade of life. The characteristic microscopic features are: the submucosal cambium layer and the presence of rhabdomyoblasts in the stroma. So far the treatment has not been well defined and ranges from conservative to radical surgery CASE: The presented case is a 22-year old woman with cervical polyp. Polypectomy with D&C was performed in 2005 and the microscopic examination revealed rhabdomyosarcoma botryoides. Detailed examination diagnosed stage 1a of the disease. The patient received 6 cycles of chemotherapy (Vincristine and Actinomycin). CONCLUSION: Conservative treatment may be considered in young women with favorable prognostic factors who wish to preserve their fertility Polypectomy followed by chemotherapy is a possible option for such patients.