Association between drinking and all-cause mortality in patients with ischemic stroke / 南方医科大学学报

OBJECTIVE@#To investigate the association between alcohol drinking and all-cause death in patients with ischemic stroke.@*METHODS@#Between January, 2010 and July, 2018, consecutive patients with first-episode ischemic stroke admitted in the West China Hospital, Sichuan University were enrolled, and all the patients were followed up every 3 months.Chi-square test was used to compare the differences in the baseline characteristics between the pre-stroke drinkers and the nondrinkers.The Cox regression model was used to analyze the effects of drinking status, drinking years, drinking frequency, average single alcohol intake before stroke and drinking status during the follow-up period on the mortality of patients after discharge.@*RESULTS@#A total of 855 patients with ischemic stroke were enrolled, and deaths occurred in 140 of these patients.Chi-square test showed significant differences in gender ( < 0.001), weekly physical exercise time (=0.035), smoking ( < 0.001), and heart disease ( < 0.001) between the pre-stroke drinkers and nondrinkers.Multivariate Cox regression analysis showed that drinking during the follow-up period (=0.001), drinking for less than 28 years before stroke (=0.035) and a moderate drinking frequency (5 to 20 times per month for males and 4 to 9 times per month for females; =0.030) were associated with a lowered risk of death after discharge.No significant effects of pre-stroke drinking status or average single alcohol intake were found on death after ischemic stroke.@*CONCLUSIONS@#The drinking years and drinking frequency before stroke and drinking status during the follow-up period are related to the all-cause mortality in patients with ischemic stroke.Investigations of the more specific variables of drinking behaviors during the follow-up period are needed to further clarify the association between drinking and death after ischemic stroke.

Study on unprotected anal intercourse behavior in HIV-positive men who have sex with men in the context of knowing their HIV infection status in Chengdu / 中华流行病学杂志

Objective To identify related factors associated with unprotected anal intercourse (UAI) among HIV-positive men who have sex with men (MSM) in the context of knowing their HIV infection status.Methods HIV positive MSM who known that they had been infected with HIV for more than 6 months and accepted follow up services were recruited by convenience sampling method in Chengdu 2015.Semi-structured questionnaire was used to collect their information,such as demographic characteristics,antiviral therapy and sexual behavior characteristics etc.Logistic regression model was used for univariate and multivariate analyses.Results A total of 330 HIV-positive MSM were recruited,201 eligible MSM were interviewed.The prevalence of UAI in recent six months was 18.41％ (37/201).The results of multivariate logistic regression analysis revealed that the number of anal intercourse with male ≥3 in last month (OR=6.22,95％CI:1.88-20.56),low education level (OR=7.29,95％CI:1.36-39.16),married,divorced or widowed status (OR=4.65,95％CI:1.13-19.17),homosexual cohabitation (OR=3.32,95％CI:1.01-10.95) were the risk factors related with UAI among the HIV-positive MSM.Conclusion Frequent homosexual anal intercourse,low education level,married,divorced or widowed status and homosexual cohabitation might be the risk factors related with UAI in HIV-positive MSM in Chengdu.

Study on unprotected anal intercourse behavior in HIV-positive men who have sex with men in the context of knowing their HIV infection status in Chengdu / 中华流行病学杂志

Objective To identify related factors associated with unprotected anal intercourse (UAI) among HIV-positive men who have sex with men (MSM) in the context of knowing their HIV infection status.Methods HIV positive MSM who known that they had been infected with HIV for more than 6 months and accepted follow up services were recruited by convenience sampling method in Chengdu 2015.Semi-structured questionnaire was used to collect their information,such as demographic characteristics,antiviral therapy and sexual behavior characteristics etc.Logistic regression model was used for univariate and multivariate analyses.Results A total of 330 HIV-positive MSM were recruited,201 eligible MSM were interviewed.The prevalence of UAI in recent six months was 18.41％ (37/201).The results of multivariate logistic regression analysis revealed that the number of anal intercourse with male ≥3 in last month (OR=6.22,95％CI:1.88-20.56),low education level (OR=7.29,95％CI:1.36-39.16),married,divorced or widowed status (OR=4.65,95％CI:1.13-19.17),homosexual cohabitation (OR=3.32,95％CI:1.01-10.95) were the risk factors related with UAI among the HIV-positive MSM.Conclusion Frequent homosexual anal intercourse,low education level,married,divorced or widowed status and homosexual cohabitation might be the risk factors related with UAI in HIV-positive MSM in Chengdu.