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1.
Nutrients ; 15(13)2023 Jun 28.
Artigo em Inglês | MEDLINE | ID: mdl-37447270

RESUMO

The present pilot study investigates the blood biochemical changes induced by hemp seeds in rats with diabetes. The composition of industrial hemp seeds, antioxidant activity, identification and quantification of phenols and fatty acids from hemp oil were determined. The Wistar adult rats used in the experiment were divided into three groups (n = 6) and kept under standard conditions. Group one, the control group (individuals without diabetes), and group two (diabetic individuals) received water and normal food ad libitum, while the third group, also including diabetic individuals, received specific food (hemp seeds) and water ad libitum. Subsequent blood biochemical parameters were determined. Hemp seeds had higher phenol (14 compounds), flavonoids and PUFA contents compared to other plants seeds. In addition, the antioxidant activity in Cannabis sativa was also increased. Moreover, the ratio between n-6 and n-3 was 4.41, ideal for different diseases. Additionally, all biochemical parameters showed significant changes following the treatment. It was shown that high doses of hemp seeds decreased diabetes-induced biochemical damage in rats most probably due to the high content of active compounds. In order to use these seeds in humans, it is essential to find out which hemp compounds are particularly responsible for these effects. Moreover, for the objective investigation of their effects, longer-term studies are needed.


Assuntos
Cannabis , Diabetes Mellitus , Humanos , Adulto , Ratos , Animais , Cannabis/química , Ratos Wistar , Antioxidantes/farmacologia , Projetos Piloto , Fenóis/análise , Sementes/química
2.
Toxics ; 11(4)2023 Mar 29.
Artigo em Inglês | MEDLINE | ID: mdl-37112550

RESUMO

Reynoutria japonica Houtt (RJ) is an extremely invasive plant species, found nowadays in a wide range of habitats, including those polluted with heavy metals (HM). The aim of this study was to investigate HM dynamics in RJ-soil interactions in five habitats historically polluted with HM located in Baia Mare city, Romania. The concentrations of major metal elements (Cd, Cu, Pb, Zn) in plant tissues (roots, stems, leaves) and soil samples collected from the study sites were analyzed via portable ED-XRF spectroscopy (converted), and the translocation factor (TF) and bioconcentration factor (BCF) were calculated. The mean values of HM in soil samples collected from the study sites exceeded the threshold limit values established by Romanian legislation. Generally, the highest concentration of Cd was recorded in the above-ground part of the plant (stem and leaves), while for Cu, Pb and Zn, the highest values (with few exceptions) were recorded in the root. The metal transfer was highly effective from soil to RJ, such that all four of the HM studied exceeded the normal range of metals in a plant. Analysis of metal concentrations in plant tissues showed an efficient movement of Cd and Zn to the above-ground parts of the plant, a tendency particularly pronounced in the case of Cd (TF and BCF > 1), while Pb was the least bioaccumulated HM. It may be concluded that RJ is able to tolerate high concentrations of HM, being a good phytoextractor for Cd and Zn.

3.
Plants (Basel) ; 12(2)2023 Jan 12.
Artigo em Inglês | MEDLINE | ID: mdl-36679071

RESUMO

Lavender is in the research spotlight due to its increasing economic importance, while market demand is expected to continue to grow. Among the hundreds of essential-oil-bearing plants, Lavandula angustifolia Mill. remains one of the most valuable. This paper explores the lavender chain timeline from crop to products, examining the expanding knowledge on the characteristics, phytochemical profile and functional potential of lavender that could lead to new products and uses. Lavender crops can be expanded without competing for productive land, instead using marginal, contaminated or unproductive land. A novel cultivation trend proposes leveraging agri-background biodiversity, arbuscular mycorrhiza and the natural enemies of pests for healthy crops. Together with breeding efforts targeting highly performant genotypes with complex volatile profiles coupled with resistance to specific biotic (particularly Phytoplasma) and abiotic (salt, heavy metals) stressors, industry could have a steady supply of high-quality raw material. Besides the expansion of the uses of essential oil in cosmetics, pharmaceuticals, food and environmental and agri-applications, novel channels have appeared for the use of the solid by-product, which is rich in polyphenols and polysaccharides; these channels have the potential to create additional streams of value. The stabilization and optimization of techno-functional delivery systems through the encapsulation of essential oil can extend shelf-life and enhance biological activity efficiency.

4.
Foods ; 10(10)2021 Oct 11.
Artigo em Inglês | MEDLINE | ID: mdl-34681450

RESUMO

Wild Rose canina fruit represents a rich source of bioactive compounds such as minerals, phenolic compounds, vitamins, carotenoids, folate, and antioxidant activity that still needs to be further exploited. Thus, this study aimed to use wild Rosa canina fruit encapsulated powder with different biopolymers aiming to manufacture ready-to-eat products, such as corn extrudates. To achieve this goal, extrudate physicochemical characteristics, such as water content (xw), water activity (aw), water absorption index (WAI), water solubility index (WSI), swelling index (SWE), hygroscopicity (Hy), expansion index (SEI), bulk density (ρb), porosity (ε), textural, optical; nutritional; and functional analysis (phenolic acids, flavonoids, ascorbic and dehydroascorbic acids, vitamin C, carotenoids, folates, antioxidant activity, and minerals) were determined. Results highlighted that 4 and 8% addition of wild Rose canina fruit encapsulated powder could be successfully used in the corn extrudates, showing the positive influence on its nutritional and functional value. Strong positive Pearson correlations were identified between antioxidant capacity and total flavonoids, carotenoids, folates, and vitamin C of mixtures and extrudates Minerals increased their amount during the extrusion process, reaching the highest values at an addition of 8% rosehip encapsulated with pea protein biopolymer. Furthermore, from the biopolymers used in the present study, pea protein powder exhibited the highest protection on the analyzed bioactive compounds against the extrusion process.

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