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Mikrobiol Z ; 61(1): 32-45, 1999.
Artigo em Russo | MEDLINE | ID: mdl-10330873

RESUMO

Experimental data have been presented which prove antibacterial efficiency of interferon preparations and inducers under infection processes evoked by Staphylococcus aureus, Salmonella typhimurium, Pseudomonas aeruginosa, Klebsiella pneumoniae. It is shown that the system of phagocytizing cells and natural cells-killers plays the basic protective role in the organism under the persistence of these microbes. The basic regularities of activating effect of interferon preparations and its inducers on the functional activity of the above mentioned cells have been found. The methods of treatment with interferon drugs based on experimental data have been developed for the first time. They were used to cure patients with pyo-septic diseases.


Assuntos
Anti-Infecciosos/uso terapêutico , Indutores de Interferon/uso terapêutico , Interferons/uso terapêutico , Animais , Infecções Bacterianas/tratamento farmacológico , Ensaios Clínicos como Assunto , Avaliação Pré-Clínica de Medicamentos , Humanos , Proteínas Recombinantes/uso terapêutico
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