[Lipid peroxidation in experimental adrenaline-induced glaucoma]. / Perekisnoe okislenie lipidov pri éksperimental'noi adrenalinovoi glaukome.

It is shown that in dynamics of the development of experimental glaucoma, simulated in rabbits, there takes place accumulation of lipid peroxidation products in the blood of animals. It is recorded that with the rise of intraocular pressure, tonographic and rheographic changes in the development of the glaucomatous process, i. e. of the glaucoma symptomatic complex, the level of lipid peroxidation becomes higher. It is emphasized that activation of lipid peroxidation as a factor of destructive changes in the eye and a body as a whole is connected with the stimulation of beta-adrenoreception in the development of the glaucomatous process.

[Cyclic nucleotides in experimental glaucoma]. / Tsiklicheskie nukleotidy pri éksperimental'noi glaukome.

cAMP and cGMP contents were studied in various eye tissues of rabbits with experimental glaucoma induced by chronic intravenous adrenaline administration. Cyclic nucleotide level was measured in the retina, choroid, iris and ciliary body. An increase in the tissue cAMP level was found especially in the iris and ciliary body. An increase in tissue cAMP content is explained by an enhanced beta-adrenergic regulation in the eyes of rabbits with experimental glaucoma. No consistent changes were found in cGMP content in eye tissues.