Incidence of urinary tract infection in neonates with septicemia: a prospective study.

AIM: The aim of this study was to investigate the incidence and clinical course of urinary tract infection (UTI) in neonates with septicemia and also determine the most common UTI manifestations in hospitalized neonates. METHODS: A cross-sectional study was carried out on consecutive febrile infants aged 1 to 56 days that were hospitalized in the neonatal intensive care unit. In all neonates with positive urine culture, scintigraphy with technetium-99m-labeled dimercaptosuccinic acid (DMSA) and ultrasonography (US) were performed. Voiding cystourethrography was performed in the course of the illness, generally within 5-7 days of hospitalization. RESULTS: Positive blood culture was detected only in 9% of patients. However, 5% of them had positive urine culture. Positive abnormal US findings were present in two of five (40%) and vesicoureteral reflux (VUR) was present in one of five (20%) of infants with positive urine culture. CONCLUSION: DMSA scan revealed renal parenchymal abnormalities in 3 of 5 (60%) neonates with urosepsis. The incidence of UTI in neonates with septicemia is low. All neonates with sepsis and positive urine culture should undergo a screening renal scintigraphy and cystogram for identifying renal parenchymal involvement and urinary tract abnormalities.

Incidence of urinary tract infection in neonates with septicemia: a prospective study.

AIM: The aim of this study was to investigate the incidence and clinical course of urinary tract infection (UTI) in neonates with septicemia and also determine the most common UTI manifestations in hospitalized neonates. METHODS: A cross-sectional study was conducted on consecutive febrile infants aged 1 to 56 days that were hospitalized in the neonatal intensive care unit. In all neonates with positive urine culture, scintigraphy with technetium-99m -labeled dimercaptosuccinic acid (DMSA) and ultrasonography (US) were done. Voiding cystourethrography was performed in the course of the illness, generally within 5-7 days of hospitalization. RESULTS: Positive blood culture was detected only in 9% of patients. However, 5% of them had positive urine culture. Positive Abnormal US findings were present in 2 of 5 (40%) and vesicoureteral reflux (VUR) was present in 1 of 5 (20%) of infants with positive urine culture. CONCLUSION: DMSA scan revealed renal parenchymal abnormalities in 3 of 5 (60%) neonates with urosepsis. The incidence of UTI in neonates with septicemia is low. All neonates with sepsis and positive urine culture should undergo a screening renal scintigraphy and cystogram for identifying renal parenchymal involvement and urinary tract abnormalities.

Ultrasonographic diagnosis of urinary tract anomalies in neonates: a study among Iranian children.

AIM: The incidence of urinary tract anomalies varies in different population and depends on several factors such as underlying etiologies. The goal of this study was to investigate the incidence of abnormal urinary tract ultrasound findings in children with different etiologies. METHODS: In a case-series study, 100 neonates who were hospitalized in the Children's Hospital Medical Center with the different etiologies such as sepsis, icter, seizure, and respiratory distress were included. In all neonates, ultrasound study was performed by using 3.5-7.5 MHz probe and neonates with the diagnosis of urinary tract infection underwent DMSA scan and voiding cystourethrogram (VCUG). RESULTS: The mean age of neonates was 10.15+/-7.45 days and 56% of patients were male. The most frequent etiologies led to hospitalization were icter (37%), sepsis (35%), and infectious respiratory distress (10%). Abnormal sonographic findings were found in 5% of patients. The frequency of urinary tract anomalies in neonates with sepsis was higher than non-septic group (14.29% versus 0.0%, P=0.008). CONCLUSION: The incidence of urinary tract anomalies which detected by sonography in our population is higher than other reported studies and has strong relationship with the occurrence of neonatal sepsis.