RESUMO
This study compared plasma zinc levels in 15 children with active pulmonary tuberculosis, 15 malnourished children and 15 healthy children. Mean plasma zinc concentrations in children with tuberculosis (71.7 microg/dL) were not significantly different than the other 2 groups (72.5 and 76.9 microg/dL). The zinc status of the children with tuberculosis was evaluated after 2 months and 4 months of DOTS therapy. The serum zinc level during anti-tuberculosis therapy decreased after 1 month and then recovered to the initial level after 4 months of treatment.
Assuntos
Antituberculosos/efeitos adversos , Transtornos da Nutrição Infantil/tratamento farmacológico , Tuberculose Pulmonar/tratamento farmacológico , Zinco , Proteínas Sanguíneas/metabolismo , Estudos de Casos e Controles , Criança , Transtornos da Nutrição Infantil/sangue , Transtornos da Nutrição Infantil/complicações , Pré-Escolar , Terapia Diretamente Observada/efeitos adversos , Monitoramento de Medicamentos , Feminino , Humanos , Lactente , Irã (Geográfico) , Masculino , Avaliação Nutricional , Estado Nutricional , Albumina Sérica/metabolismo , Estatísticas não Paramétricas , Fatores de Tempo , Resultado do Tratamento , Tuberculose Pulmonar/complicações , Zinco/sangue , Zinco/deficiênciaRESUMO
This study compared plasma zinc levels in 15 children with active pulmonary tuberculosis, 15 malnourished children and 15 healthy children. Mean plasma zinc concentrations in children with tuberculosis [71.7 microg/dL] were not significantly different than the other 2 groups [72.5 and 76.9 microg/dL]. The zinc status of the children with tuberculosis was evaluated after 2 months and 4 months of DOTS therapy. The serum zinc level during anti-tuberculosis therapy decreased after 1 month and then recovered to the initial level after 4 months of treatment
