[Colposcopy and cervical biopsy in patients with routine Papanicolaou smear]. / Colposcopía y biopsia cervical en pacientes con papanicolaou de rutina.

The objective of this report was to assess the sensitivity and specificity of Pap smear and to evaluate if routine colposcopy can improve cervical screening. One hundred and fifty patients undergoing routine cervical cytologic screening in our outpatient clinic were randomly selected. All patients were evaluated by colposcopy and cervical punch biopsy. Pap smears and biopsies specimens were interpreted independently. Colposcopy was performed and interpreted without knowledge of cytologic or histologic findings. The statistical analysis was carried out with a chi square (chi 2) test. A P value of less than 0.05 was considered significant. Twenty three patients (15.3%) who had biopsy proved to have cervical pathology. Pap smear identified only 4/23 (17%) of these patients. Colposcopy noted atypical transformation zones in 20/23 (97%), P < 0.001). Fifteen of 27 patients (55.5%) with negative Pap smears had colposcopic anormalities and histologically proved cervical intraepithelial neoplasia (CIN). We concluded that it is necessary to improve sensitivity and that colposcopy may enhance cervical screening particularly in women with otherwise negative Papapnicolaou smears.

[Diathermic loop treatment of subclinical cervical infection by human papilloma virus (HPV). Short-term effectiveness]. / Tratamiento de la infección cervical subclínica por el virus del papiloma humano (VPH) con asa diatérmica. Eficacia a corto plazo.

Multiple modalities of treatment have been employed since cervical subclinical papillomavirus (SPI) were discovered, with various degrees of success. The objective of this report is to assess the efficacy of the removal of cervical SPI by mean of LEEP in office conization. During the period from January 1992 and December 1993, 49 patients with histologically proven HPV infection were treated at the Private Colposcopic Clinic with LEEP. Patients ages ranged from 20 to 49 years old with average 36.1 years, mostly were parous woman. Satisfactory specimens suitable for histologic examination was obtained and in all cases margins of excisions appeared histologically clear of HPV infections patients discomfort was none or minimal in 45 patients (91.8%) and moderate in 4 (8.1%). There were 5 cases (10.2%) of postoperative haemorrhage and 3 cases (6.1%) of minimal cervical infections. The mean base of cone biopsy was 1.43 cm, and ranged from 1.0 to 3.0 cm. The overall cure rate of LEEP was 98% because there was only one confirmed case of treatment failures by loop conization. We concluded that this term results are satisfactory.