RESUMO
Although pyoctanin is widely used in medicine, there are hardly any reports of contact allergy to it. Most reports of side-effects refer to irritant reactions after topical application. We describe 2 patients who developed pyoctanin contact dermatitis after long-term application on damaged skin. Positive patch test results down to concentrations of 0.0025% and 0.05% aqueous pyoctanin solution, respectively, were found.
Assuntos
Anti-Infecciosos Locais/efeitos adversos , Dermatite Alérgica de Contato/etiologia , Violeta Genciana/efeitos adversos , Administração Tópica , Corticosteroides/uso terapêutico , Anti-Infecciosos Locais/administração & dosagem , Anti-Infecciosos Locais/uso terapêutico , Dermatite Alérgica de Contato/diagnóstico , Dermatite Alérgica de Contato/tratamento farmacológico , Dermatoses do Pé/diagnóstico , Dermatoses do Pé/tratamento farmacológico , Violeta Genciana/administração & dosagem , Violeta Genciana/uso terapêutico , Humanos , Dermatoses da Perna/diagnóstico , Dermatoses da Perna/tratamento farmacológico , Masculino , Pessoa de Meia-Idade , Dermatopatias Papuloescamosas/diagnóstico , Dermatopatias Papuloescamosas/tratamento farmacológico , Tinha dos Pés/diagnóstico , Tinha dos Pés/tratamento farmacológicoRESUMO
Localized cicatricial pemphigoid of the Brunsting-Perry type is a very rare bullous condition, which has so far been reported in 51 cases. It is characterized by scarring blisters confined to the head, scalp and neck. Diagnosis can be difficult because of the discrete skin lesions, often repeatedly false-negative direct immunofluorescence, and the absence of circulating antibodies. We report on a 87-year-old male patient with the typical clinical feature of a cicatricial pemphigoid of the Brunsting-Perry type and give a review of the 51 cases published in the world literature.
