1.
Org Lett
; 16(3): 724-6, 2014 Feb 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24433154
RESUMO
The first examples of gold-catalyzed cyclizations of diols and triols to the corresponding hetero- or spirocycles in an aqueous medium are presented. These reactions take place within nanomicelles, where the hydrophobic effect is operating, thereby driving the dehydrations, notwithstanding the surrounding water. By the addition of simple salts such as sodium chloride, reaction times and catalyst loadings can be significantly decreased.
Assuntos
Álcoois/química , Ouro/química , Cloreto de Sódio/química , Água/química , Catálise , Ciclização , Micelas , Estrutura Molecular , Temperatura
2.