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1.
Biomimetics (Basel) ; 9(3)2024 Mar 07.
Artigo em Inglês | MEDLINE | ID: mdl-38534850

RESUMO

This article contains the results of identifying the potential of coniferous trees to act as bioinspiration for the structural design of columns in single-story warehouses subjected to high wind velocity and severe seismic action. This study starts by analyzing the biomechanics of coniferous trees, continues with an abstraction of the relevant features, and ends with the transfer of a design methodology for long reinforced and prestressed concrete columns. To verify the applicability and validity of the mathematical relationships extracted from the bibliographic study to characterize the biomechanics of coniferous trees, a study site is conducted for Norway spruce trees felled by the wind in the Bilbor area. The design methodology for long reinforced and prestressed concrete columns bioinspired by the Norway spruce trees is experimentally validated using two case studies. The first case study deals with the effect of centric prestressing on long concrete columns, and the second on the influence of the walnut shell powder on the adhesion of the reinforcement in concrete. The case studies presented aim to transfer some characteristics from trees to reinforced concrete to improve the performance of long columns under horizontal forces. The results obtained indicate a good approximation of the trees' structural behavior for this site and for ones investigated by other researchers in different forests.

2.
Materials (Basel) ; 14(17)2021 Aug 30.
Artigo em Inglês | MEDLINE | ID: mdl-34501041

RESUMO

Crystalline admixtures embedded in concrete may react in the presence of water and generate thin crystals able to fill pores, capillaries and micro-cracks. Once the concrete has dried, the crystalline chemicals sit dormant until another dose of water starts the crystallization again. The research aims to analyses the early age self-sealing effect of a crystalline admixture at a dosage rate of 1-3% of the cement mass. Specimens made with two types of gravel were pre-loaded with three-point bending to up to 90% of the ultimate capacity, and conditioned through wet-dry cycles. Micro-crack closure was measured with a microscope after pre-loading, and after 1 day, 4 days, 8 days, 14 days and 20 days of wet-dry exposure. The results show that an admixture content of 3% achieves the best early self-sealing performance. These results are also confirmed by probabilistic analyses, which also emphasize the self-sealing potential of lower ICW contents.

3.
J Vasc Surg ; 70(1): 208-215, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-30792061

RESUMO

BACKGROUND: Inflammation is a cardiovascular risk factor in hemodialysis patients, but its influence on vascular access patency is still debatable. Our prospective study investigated this issue. METHODS: A total of 258 patients receiving an arteriovenous fistula (AVF) between 2006 and 2016 at the Municipal Hospital Arad were included. Demographic, clinical, and laboratory characteristics were collected at the time of creation of the AVF. The primary study end point was AVF patency loss, defined as an event occurring at least 2 months after AVF formation and requiring surgical revision or replacement of the fistula. The patients were followed up for a median time of 26 months. RESULTS: In our group, the mean age was 59.7 ± 13.2 years (median, 62 years), and 60.1% were male. During follow-up, 134 patients (51.9%) maintained AVF patency, whereas 124 (48.1%) lost AVF patency within a mean time of 23.3 ± 28.1 months (median, 10.5 months). We found that age (hazard ratio [HR], 1.015; P = .035) and C-reactive protein (CRP) level (HR, 1.17; P < .0001) were associated with a higher risk of loss of AVF patency. The protective factors for AVF patency were autosomal dominant polycystic kidney disease (HR, 0.336; P = .009), pre-emptive AVF (HR, 0.648; P = .031), and higher level of triglycerides (HR, 0.998; P = .035). In the multivariate adjusted Cox model, CRP level remained an independent predictor for loss of AVF patency (HR, 1.17; 95% confidence interval, 1.1-1.3; P < .0001). CONCLUSIONS: In our study, CRP level was an independent predictor of AVF patency loss, whereas better AVF survival was independently associated with autosomal dominant polycystic kidney disease and pre-emptive AVF. As a simple noninvasive marker of chronic inflammation, CRP level may be a useful tool to predict AVF outcomes. Further research is needed to assess the protective effects of inflammation reduction on AVF survival.


Assuntos
Derivação Arteriovenosa Cirúrgica/efeitos adversos , Proteína C-Reativa/metabolismo , Oclusão de Enxerto Vascular/etiologia , Mediadores da Inflamação/sangue , Diálise Renal , Adulto , Idoso , Idoso de 80 Anos ou mais , Biomarcadores/sangue , Feminino , Oclusão de Enxerto Vascular/sangue , Oclusão de Enxerto Vascular/fisiopatologia , Oclusão de Enxerto Vascular/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Valor Preditivo dos Testes , Estudos Prospectivos , Reoperação , Medição de Risco , Fatores de Risco , Romênia , Fatores de Tempo , Resultado do Tratamento , Grau de Desobstrução Vascular
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