RESUMO
The results of the prolonged epidemiological surveillance on measles in Moscow are presented. The detailed analysis of the influence of immunization on the level of measles morbidity has been made. Changes in the age structure of measles patients with an essential increase in the proportion of adolescents and adults due to mass vaccination of the child population are shown. High risk groups have been determined according to the data of serological screening and epidemiological surveillance. The prospects of the vaccinal prophylaxis of measles under present conditions, as the basic intervention for achieving sporadic level of morbidity in this infection and further eradication are evaluated.
Assuntos
Vacina contra Sarampo/administração & dosagem , Sarampo/prevenção & controle , Humanos , Sarampo/epidemiologia , Moscou/epidemiologia , Vigilância da PopulaçãoRESUMO
The potentialities of computers for the study of the effectiveness of immunization have been demonstrated and the mathematical model for the prediction of the proportion of children, seronegative to measles, derived on the basis of the data on the average measles morbidity in different groups for a given period. A multifactor analysis of a large scope of data obtained in seroepidemiological survey and a retrospective analysis of measles morbidity on the basis of data collected in two districts of Moscow have been carried out with the use of computers and mathematical methods.