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1.
Rev Sci Instrum ; 84(7): 075116, 2013 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-23902115

RESUMO

A high-speed impact testing method for evaluating mechanical properties of materials is proposed using an inertial mass and a dual beat-frequencies laser Doppler interferometer (DB-LDI). In this method, an inertial mass levitated using an aerostatic linear bearing is made to collide with the material being tested at a high initial velocity. During the collision, the velocity of the mass, which is even higher than the critical velocity (±0.56 m/s) defined by the frequency difference of the Zeeman laser, is accurately measured using the DB-LDI. The position, acceleration, and impact force of the mass are calculated from the measured velocity. Using the proposed method, the mechanical properties of a visco-elastic material under a high-speed impact loading condition can be accurately evaluated.

2.
IEEE Trans Nanobioscience ; 12(3): 228-32, 2013 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-23686955

RESUMO

Magnetic therapy is an alternative medicine practice involving the use of magnetic fields subjected to certain parts of the body and stimulates healing from a range of health problems. In this paper, an embedded nano-antenna system using the optical spins generated from a particular configuration of microrings (PANDA) is proposed. The orthogonal solitons pairs corresponding to the left-hand and right-hand optical solitons (photons) produced from dark-bright soliton conversion can be simultaneously detected within the system at the output ports. Two possible spin states which are assigned as angular momentum of either +h or -h will be absorbed by an object whenever this set of orthogonal solitons is imparted to the object. Magnetic moments could indeed arise from the intrinsic property of spins. By controlling some important parameters of the system such as soliton input power, coupling coefficients and sizes of rings, output signals from microring resonator system can be tuned and optimized to be used as magnetic therapy array.


Assuntos
Magnetoterapia/instrumentação , Modelos Teóricos , Nanomedicina/instrumentação , Pinças Ópticas , Fótons
3.
Artif Cells Nanomed Biotechnol ; 41(1): 21-6, 2013 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-22992006

RESUMO

This paper proposes a nano-antenna system using the optical spins generated by a PANDA ring resonator for radio therapeutic applications. Initially, the magnetic field is induced by the coupling effects between aluminium plate (Al) and TE and TM light modes. The generated electromagnetic wave radiation is controlled by a soliton power, coupling coefficients, and ring radii within the system, where finally the near field radio wave is transmitted to the required therapeutic target (neural cells). Simulation results have shown that the temperature within the range from 40°C to about 46°C can be controlled and achieved.


Assuntos
Nanoestruturas , Neoplasias/radioterapia , Neurônios/efeitos da radiação , Dispositivos Ópticos , Espectroscopia de Ressonância de Spin Eletrônica/métodos , Humanos , Ondas de Rádio , Temperatura
4.
Int J Nanomedicine ; 6: 2385-92, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-22072875

RESUMO

This investigation proposes the use of molecular network topology for drug delivery and diagnosis network design. Three modules of molecular network topologies, such as bus, star, and ring networks, are designed and manipulated based on a micro- and nanoring resonator system. The transportation of the trapping molecules by light in the network is described and the theoretical background is reviewed. The quality of the network is analyzed and calculated in terms of signal transmission (ie, signal to noise ratio and crosstalk effects). Results obtained show that a bus network has advantages over star and ring networks, where the use of mesh networks is possible. In application, a thin film network can be fabricated in the form of a waveguide and embedded in artificial bone, which can be connected to the required drug targets. The particular drug/nutrient can be transported to the required targets via the particular network used.


Assuntos
Sistemas de Liberação de Medicamentos/instrumentação , Sistemas de Liberação de Medicamentos/métodos , Técnicas de Diagnóstico Molecular/instrumentação , Técnicas de Diagnóstico Molecular/métodos , Nanomedicina/instrumentação , Nanomedicina/métodos , Humanos , Modelos Teóricos , Rede Nervosa , Pinças Ópticas , Processamento de Sinais Assistido por Computador , Razão Sinal-Ruído
5.
Int J Nanomedicine ; 6: 1757-64, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-21980238

RESUMO

A novel design of a multi-drug delivery network and diagnosis using a molecular network is proposed. By using a pair of tweezers to generate the intense optical vortices within the PANDA ring resonator, the required molecules (drug volumes) can be trapped and moved dynamically within the molecular bus networks, in which the required drug delivery targets can be achieved within the network. The advantage of the proposed system is that the diagnostic method can be used within a tiny system (thin film device or circuit), which is available as an embedded device for diagnostic use in patients. In practice, the large molecular networks such as ring, star, and bus networks can be integrated to form a large drug delivery system. The channel spacing of the trapped volumes (molecules) within the bus molecular networks can be provided by using the appropriate free spectrum range, which is analyzed and discussed in the terms of crosstalk effects. In this work, crosstalk effects of about 0.1% are noted, which can be neglected and does not affect the network stability.


Assuntos
Sistemas de Liberação de Medicamentos/métodos , Modelos Biológicos , Nanomedicina/instrumentação , Pinças Ópticas , Vasos Sanguíneos/metabolismo , Sistemas de Liberação de Medicamentos/instrumentação , Humanos , Microtúbulos/metabolismo , Neurônios/metabolismo
6.
Int J Nanomedicine ; 6: 1209-16, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-21822383

RESUMO

A novel design of an optical trapping tool for tangle protein (tau tangles, ß-amyloid plaques) and molecular motor storage and delivery using a PANDA ring resonator is proposed. The optical vortices can be generated and controlled to form the trapping tools in the same way as the optical tweezers. In theory, the trapping force is formed by the combination between the gradient field and scattering photons, and is reviewed. By using the intense optical vortices generated within the PANDA ring resonator, the required molecular volumes can be trapped and moved dynamically within the molecular buffer and bus network. The tangle protein and molecular motor can transport and connect to the required destinations, enabling availability for Alzheimer's diagnosis.


Assuntos
Doença de Alzheimer/diagnóstico , Modelos Biológicos , Técnicas de Diagnóstico Molecular/instrumentação , Nanomedicina/métodos , Pinças Ópticas , Peptídeos beta-Amiloides/química , Sistemas de Liberação de Medicamentos , Humanos , Microtúbulos , Técnicas de Diagnóstico Molecular/métodos , Emaranhados Neurofibrilares , Placa Amiloide/química , Tubulina (Proteína)/química , Proteínas tau/química , Proteínas tau/isolamento & purificação
7.
J Nanosci Nanotechnol ; 11(12): 10449-53, 2011 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-22408924

RESUMO

A novel design of all-optical logic device is proposed. An all-optical logic device system composes of an optical intensity switch and add/drop filter. The intensity switch is formed to switch signal by using the relationship between refraction angle and signal intensity. In operation, two input signals are coupled into one with some coupling loss and attenuation, in which the combination of add/drop with intensity switch produces the optical logic gate. The advantage is that the proposed device can operate the high speed logic function. Moreover, it uses low power consumption. Furthermore, by using the extremely small component, this design can be put into a single chip. Finally, we have successfully produced the all-optical logic gate that can generate the accurate AND and NOT operation results.

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