A rise in activity of natural cold isolymphocytotoxins after hemostimulation.

Natural cold isolymphocytotoxins (NCILCT) were studied in sera of patients with chronic renal insufficiency who had undergone 3-200 hemodialyses, in sera of healthy subjects before and after intramuscular injections of 5-9 ml of whole autologous blood, and in sera of hemophilia patients before and after a transfusion of 130-250 ml of freshly drawn donor plasma concentrate. It was noted NCILCT activity rose from 20-50% to 50-100% dead cells after injections of autologous blood and plasma transfusions in the majority of cases. In subjects who had undergone hemodialysis from 50 to 200 time NCILCT activity was considerably higher (50-80% dead cells) compared to patients with 3-10 hemodialyses (20-30% dead cells). It was suggested that the graft protection effect of blood transfusions and hemodialysis on kidney graft may be associated with an increase in NCILCT activity.

[Increase in the level of cold lymphocytotoxins in the blood serum after autohemostimulation]. / Povyshenie urovnia kholodnyky limfotsitotoksinov v syvorotke krovi posle autogemostimuliatsii.

Activity of natural cold isolymphocytotoxins (NCILCT) was studied in the serum of 16 volunteers who received whole auto blood injections. Autohemostimulation was shown to result in the increased activity of NCILCT. The evidence obtained allowed the conclusion that autohemostimulation can be used for preparation of active NCILCT test sera.