RESUMO
1- Primary tuberculoid leprosy is a manifestation of power of resistance against the leprosy bacillus on the part of the infected individual. At this stage of the disease, suitable treatment will prevent its transforming to lepromatous leprosy. 2- The infiltrations and nodules of lepromatous leprosy, under treatment, are gradually absorbed, and the bacilli in the lepra cells are changed to lipoid granules. When that happens, there is evidence of the individual's recovery of the power of resistance in the change of lepromin reactivity from negative to positive. 3- The histopathology of the positive leproma-reaction nodule in the "secondary neural" case corresponds to that of the tissue granuloma of tuberculoid leprosy. For this reason I advocate calling such cases "secondary tuberculoid". 4- The positive lepromin reaction should be determined by the delayed reaction, the lesion of which shows the tuberculoid histology.
Assuntos
Hanseníase , Hanseníase Tuberculoide/diagnósticoRESUMO
When leprosy and tuberculosis attack the same organ we often find Langhans giant cells which contain bacilli of both kinds. Tuberculosis-like changes in leprous macules, tuberculoid macules and neural changes indicate the resistence of the body to the bacilli. The same histopathological changes can be seen in Mitsuda's skin reaction. Langhans giant cells may also be seen in the skin, testicle and epididymis in nocular cases. These differ from giant cells of the other type (a) in having a lower degree of foamy reaction, and (b) in the presence of one or more stellate bodies which can be stained with elastic-tissue or Bielschowsky's stain.
