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1.
BJPsych Int ; 17(4): 95-96, 2020 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-33196700

RESUMO

The European Psychiatric Association (EPA), the main association in the field of mental health in Europe, has long been supporting the development of early career psychiatrists. The EPA Early Career Psychiatrists Committee (ECPC) and its core task forces promote research activities among young psychiatrists, contribute to their professional development through organising courses and other educational events, prepare online educational materials and publications, and actively collaborate with other organisations. The EPA ECPC is always open to fostering cooperation on new professional, educational or research initiatives with early career psychiatrists from different countries.

4.
Am J Physiol Endocrinol Metab ; 294(3): E576-81, 2008 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-18198350

RESUMO

Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disturbance among women of reproductive age and is proposed to be linked with size at birth and increased prevalence of cardiovascular disease. A disturbance in the sympathetic nervous system may contribute to the etiology of PCOS. This study evaluates sympathetic outflow in PCOS and its relation to size at birth. Directly recorded sympathetic nerve activity to the muscle vascular bed (MSNA) was obtained in 20 women with PCOS and in 18 matched controls. Ovarian ultrasonographic evaluation, biometric, hormonal, and biochemical parameters were measured, and birth data were collected. Women with PCOS had increased MSNA (30 +/- 8 vs. 20 +/- 7 burst frequency, P < 0.0005) compared with controls. MSNA was positively related to testosterone (r = 0.63, P < 0.005) and cholesterol (r = 0.55, P = 0.01) levels in PCOS, which, in turn, were not related to each other. Testosterone level was a stronger predictor of MSNA than cholesterol. Birth size did not differ between the study groups. This is the first study to directly address sympathetic nerve activity in women with PCOS and shows that PCOS is associated with high MSNA. Testosterone and cholesterol levels are identified as independent predictors of MSNA in PCOS, although testosterone has a stronger impact. The increased MSNA in PCOS may contribute to the increased cardiovascular risk and etiology of the condition. In this study, PCOS was not related to size at birth.


Assuntos
Peso ao Nascer/fisiologia , Síndrome do Ovário Policístico/fisiopatologia , Sistema Nervoso Simpático/fisiopatologia , Doenças Cardiovasculares/etiologia , Colesterol/sangue , Feminino , Hormônio Foliculoestimulante/sangue , Humanos , Recém-Nascido , Hormônio Luteinizante/sangue , Músculos/inervação , Síndrome do Ovário Policístico/complicações , Gravidez , Análise de Regressão , Globulina de Ligação a Hormônio Sexual/análise , Testosterona/sangue
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